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https://www.selleckchem.com/products/CP-690550.html Clinical Relevance- Automated cuffless BP monitoring is opening a new chapter in the way patients are being diagnosed and managed. This paper provides a guidance on how to assess the clinical utility of such devices when used in different body positions.Visceral congestion and edema are important features of advanced heart failure. Monitoring the evolution of fluid content in the gastric wall might provide an index of the development of this phenomenon and therefore constitute an innovative marker to early detect acute decompensated heart failure episodes. The evolution of the fluid content in the gastric wall is measured using a device implanted in the submucosa layer of the fundic region of the stomach. The device composed of two electrodes measures the bioimpedance values that reflects the water content of the tissue.An in-vivo experiment in a pig was carried out to validate the feasibility of detecting the gastric bioimpedance variations during the development of an experimental acute visceral edema caused by an endotoxemic shock. Our preliminary results confirm the possibility to monitor the bioimpedance variations due to moderate changes in tissue water content (10%) with a two-electrode configuration device implanted in the submucosa of the stomach.We present an open-source, low-cost, portable, 128-channel bioamplifier module designed specifically for ambulatory, long-term (≥24 hr) monitoring of gastrointestinal (GI) electrical activity. The electronics hardware integrates stateof-the-art, commercial-off-the-shelf components on a custom PCB. Features include on-board data logging, wireless data streaming, subject motion monitoring, and stable operation up to the maximum 2 kHz/channel sampling rate tested. The new device operates for ≈ 30 hr continuously powered by a single 3.7 V, 2500 mAh LiPo battery. The 3D-printed ABS mechanical enclosure is robust and small (13.1 × 8.8 × 2.5 cm), so that the device can b

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