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https://www.selleckchem.com/products/amredobresib.html The ability to reliably grasp and manipulate novel objects is a grand challenge for robotics.Scifi assumes creating a robot mother will be easy, research indicates otherwise, but both suggest you might not want one anyway.Tactile feedback is a natural pathway to robot dexterity in unstructured settings.Policy gradient methods can be used for mechanical and computational co-design of robot manipulators.The process of modeling a series of hand-object parameters is crucial for precise and controllable robotic in-hand manipulation because it enables the mapping from the hand's actuation input to the object's motion to be obtained. Without assuming that most of these model parameters are known a priori or can be easily estimated by sensors, we focus on equipping robots with the ability to actively self-identify necessary model parameters using minimal sensing. Here, we derive algorithms, on the basis of the concept of virtual linkage-based representations (VLRs), to self-identify the underlying mechanics of hand-object systems via exploratory manipulation actions and probabilistic reasoning and, in turn, show that the self-identified VLR can enable the control of precise in-hand manipulation. To validate our framework, we instantiated the proposed system on a Yale Model O hand without joint encoders or tactile sensors. The passive adaptability of the underactuated hand greatly facilitates the self-identification process, because they naturally secure stable hand-object interactions during random exploration. Relying solely on an in-hand camera, our system can effectively self-identify the VLRs, even when some fingers are replaced with novel designs. In addition, we show in-hand manipulation applications of handwriting, marble maze playing, and cup stacking to demonstrate the effectiveness of the VLR in precise in-hand manipulation control.The ever-changing nature of human environments presents great challenges to rob

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