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https://www.selleckchem.com/products/xl413-bms-863233.html ernal-fetal complications. We discuss the latest options in antiviral therapy and vaccine development, including the novel use of chloroquine in the management of COVID-19. Fetal surveillance, in view of the predisposition to growth restriction and special considerations during labor and delivery are addressed. Additionally, we focus on keeping frontline obstetric care providers safe while continuing to provide essential services. Our clinical service model is built around the principles of workplace segregation, responsible social distancing, containment of cross-infection to healthcare providers, judicious use of personal protective equipment and telemedicine. Our aim is to share a framework which can be adopted by tertiary maternity units managing pregnant women in the flux of a pandemic while maintaining the safety of the patient and healthcare provider at its core. BACKGROUND AND AIMS A prior randomized study (Surveillance versus Radiofrequency Ablation study [SURF study]) demonstrated that radiofrequency ablation (RFA) of Barrett's esophagus (BE) with confirmed low-grade dysplasia (LGD) significantly reduces the risk of esophageal adenocarcinoma. Our aim was to report the long-term outcomes of this study. METHODS The SURF study randomized BE patients with confirmed LGD to RFA or surveillance. For this retrospective cohort study, all endoscopic and histological data acquired after end of the SURF study in May 2013 until December 2017 were collected. The main outcome was rate of progression to HGD/cancer. All 136 patients randomized to RFA (n=68) or surveillance (n=68) in the SURF study were included. After closure of the SURF study, 15 surveillance patients underwent RFA based on the patient's preference and the outcomes of the study RESULTS With 40 (IQR 12-51) additional months, the total median follow-up from randomization to last endoscopy was 73 (IQR 46-85) months. HGD/cancer was diagnosed in 1 pati

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