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https://www.selleckchem.com/products/sgc707.html Anthropophilic female mosquitoes are well known for their strong attraction to human hosts, but plant nectar is a common energy source in their diets. When sugar sources are scarce, female mosquitoes of some species can compensate by taking larger and more frequent blood meals. Male mosquitoes are exclusively dependent on plant nectar or alternative sugar sources. Plant preference is likely driven by an innate attraction that may be enhanced by experience, as mosquitoes learn to recognize available sugar rewards. Nectar-seeking involves the integration of at least three sensory systems olfaction, vision and taste. The prevention of vector-borne illnesses, the determination of the mosquitoes' ecological role, and the design of efficient sugar-baited traps will all benefit from understanding the molecular basis of nectar-seeking. Inflammasomes are cytosolic complexes that assemble in response to cellular stress or upon sensing microbial molecules, culminating in cytokine processing and an inflammatory form of cell death called pyroptosis. Inflammasomes are usually composed of a sensor molecule, an adaptor protein, and an inflammatory caspase, such as Caspase-1, which cleaves and activates multiple substrates, including Gasdermin-D, pro-IL-1β, and pro-IL-18. Ultimately, inflammasome activation promotes inflammation and restriction of the microbial infection. In recent years, many studies have addressed the role of inflammasomes during fungal, bacterial, viral, and parasitic diseases, revealing sophisticated aspects of the host-pathogen interaction. In this review, we summarize recent advances on inflammasome activation in response to intracellular parasites, including Leishmania spp., Plasmodium spp., Trypanosoma cruzi, and Toxoplasma gondii. Estimation of Plasmodium vivax biomass based on circulating biomarkers indicates the existence of a predominant biomass outside of the circulation that is not captured by peripheral

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