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https://www.selleckchem.com/products/Mycophenolic-acid(Mycophenolate).html © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.The specific gold-sulfur binding interaction renders gold complexes to be promising anti-cancer agents that can potentially overcome cisplatin resistance; while their unbiased binding towards non-tumoral off-target thiol-proteins has posed a big hurdle to clinical application. Herein we report that cyclometalated gold(III) complexes bearing hydride ligands are highly stable towards thiols in the dark but can efficiently dissociate the auxiliary hydride moiety and generate gold-thiol adduct when excited with visible light. In consequence, the photo-activated gold(III) complexes potently inhibited thioredoxin reductase in association with up to >400-fold increment of photocytotoxicity (vs dark condition) without deactivation by serum albumin and along with strong anti-angiogenesis activity in zebrafish embryos. Importantly, the gold(III)-hydride complexes could be activated by two-photon laser irradiation at the phototherapeutic window as effectively as blue light irradiation. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.Octacyanometallates K 4 [Mo(CN) 8 ] and K 4 [W(CN) 8 ] are completely protonated in superacidic mixtures of anhydrous hydrogen fluoride and antimony pentafluoride. The resulting hydrogen isocyanide complexes [Mo(CNH) 8 ] 4+ [SbF 6 ] - 4 and [W(CNH) 8 ] 4+ [SbF 6 ] - 4 are the first examples of eight-coordinate homoleptic metal complexes containing hydrogen isocyanide (CNH) ligands. The complexes were crystallographically characterized, revealing hydrogen-bonded networks with short N … H … F contacts. Low-temperature NMR measurements in HF confirmed rapid proton exchange even at -40 °C. Upon protonation, ṽ(C≡N) increases of about 50 cm -1 which is in agreement with DFT-calculations. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.Elastin-like polypeptides (ELPs) have been proposed as a simple model of intrinsically disorde

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