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https://www.selleckchem.com/products/alizarin-red-s.html 73 folds in stable working time.Poor efficacy and low electrical safety are issues in the treatment of tumours with pulsed magnetic fields (PMFs). Based on the cumulative effect of high-frequency pulses and the enhanced perforation effect of targeted nanoparticles, this article proposes for the first time a new method that combines high-frequency nanosecond-pulsed magnetic fields (nsPMFs) with folic acid-superparamagnetic iron oxide nanoparticles (SPIONs-FA) to kill tumour cells. After determining the safe concentration of the targeted iron oxide nanoparticles, CCK-8 reagent was used to detect the changes in cell viability after utilising the combined method. After that, PI macromolecular dyes were used to stain the cells. Then, the state of the cell membrane was observed by scanning electron microscopy, and other methods were applied to study the cell membrane permeability changes after the combined treatment of the cells. It was finally confirmed that the high-frequency PMF can significantly reduce cell viability through the cumulative effect. In addition, the targeted iron oxide nanoparticles can reduce the magnetic field amplitude and the number of pulses required for the high-frequency PMF to kill tumour cellsin vitrothrough magnetoporation. The objective of this research is to improve the electrical safety of the PMF with the use of nsPMFs for the safe, efficient and low-intensity treatment of tumours.The Landau-Lifshitz-Gilbert (LLG) equation, used to model magneto-dynamics in ferromagnets, tacitly assumes that the angular momentum associated with spin precession can relax instantaneously when the real or effective magnetic field causing the precession is turned off. This neglect of 'spin inertia' is unphysical and would violate energy conservation. Recently, the LLG equation was modified to account for inertia effects. The consensus, however, seems to be that such effects would be unimportant inslowmag

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