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https://www.selleckchem.com/products/wortmannin.html BACKGROUND Gonorrhea is a significant public health concern. The changing epidemiology of gonorrhea in Australia has highlighted the need for detailed examination of surveillance data to determine population groups at greatest risk for infection. METHODS We analysed de-identified gonorrhea notification data for the years 2012 to 2017, in Adelaide (N=3,680), calculating age-adjusted notification and antibiotic resistance rates. Age, sex, year, sexual orientation and socioeconomic status were assessed for associations with gonorrhea notifications using negative binomial, log binomial and spatial autoregressive models. Maps were generated to examine spatial localization of gonorrhea rates in Adelaide. RESULTS Gonorrhea notification rates in Adelaide increased annually, with a 153% adjusted increase in rates from 2012 to 2017, localized to specific areas and inversely associated with income levels. The increase in rates in 2016 and 2017 was associated with young heterosexuals from low income areas. Azithromycin resistant notifications increased significantly in 2016 in young heterosexuals. Re-infections were significantly more likely in men who have sex with men (MSM) than other population groups. CONCLUSIONS This study demonstrates the changing epidemiology of gonorrhea in Adelaide from a largely MSM profile towards an increase in young heterosexual gonorrhea. This could be seen as a harbinger for future increases in heterosexually transmitted HIV and other STIs in Australia.INTRODUCTION Medical school offices of faculty development aim to facilitate the academic growth of junior faculty by fostering independent research, enhancing teaching skills, and bolstering career opportunities. The Rush Research Mentoring Program aims to achieve this goal at Rush University medical center by offering a broad resource armamentarium and creating an environment that fosters productive relationships between mentees and mentors. Th

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