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https://www.selleckchem.com/products/rp-6685.html Titanium (Ti) has excellent biocompatibility and corrosion resistance and is widely used as a biomedical material for orthopedic implants. However, the bare Ti surface limits cell adhesion without biological activity and promotes unnecessary protein adsorption, which can activate the coagulation pathway with blood-contacting devices. To improve the antifouling and biological activity of Ti, zwitterionic poly[2-(methacryloyloxy)ethyl choline phosphate] (PMCP) was used to modify the Ti surface via surface-initiated atom transfer radical polymerization. The Ti-PMCP surface reduced bovine serum albumin and fibrinogen adsorption owing to the zwitterionic antifouling property. Ti-PMCP is involved in the unique interaction between PMCP on the Ti surface and phosphate choline on cell membranes, and therefore, the Ti-PMCP surface can promote the adhesion and proliferation of MC3T3-e1 cells and bone marrow mesenchymal cells (BMSCs). In addition, the Ti-PMCP surface was effective in promoting the osteogenic differentiation of MC3T3-e1 cells and BMSCs because the phosphate group in MCP can stimulate osteogenic signaling pathways. Therefore, the PMCP-modified Ti surface can resist protein adsorption and promote the adhesion, proliferation, and differentiation of osteoblast-related cells and has great potential in bone tissue engineering.Terrestrial soils are not only a large reservoir for Microplastics (MPs), but also a possible entrance to the subsurface environment, posing potential risks to the subterranean habitats and groundwater. In this study, we examined the vertical transport of MPs of four polymers, i.e., polyethylene (PE), polyethylene terephthalate (PET), polypropylene (PP) and polyamide (PA), in porous sand media driven by wet-dry cycling. The effects of polymer properties, MP size, sand particle size, wet-dry cycles, and dissolved organic matter (DOM) on their migration behavior were investigated. Surface hydrophobi

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