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https://www.selleckchem.com/MEK.html OBJECTIVES Treatment in a disproportionately minority-serving hospital has been associated with worse outcomes in a variety of illnesses. We examined the association of treatment in disproportionately minority hospitals on outcomes in patients with sepsis across the United States. DESIGN Retrospective cohort analysis. Disproportionately minority hospitals were defined as hospitals having twice the relative minority patient population than the surrounding geographical mean. Minority hospitals for Black and Hispanic patient populations were identified based on U.S. Census demographic information. A multivariate model employing a validated algorithm for mortality in sepsis using administrative data was used. SETTING The National Inpatient Sample from 2008 to 2014. PATIENTS Patients over 18 years of age with sepsis. INTERVENTIONS None. MEASUREMENTS AND MAIN RESULTS A total of 4,221,221 patients with sepsis were identified. Of these, 612,217 patients (14.5%) were treated at hospitals disproportionately serving the black community (Black hospitals), whereas 181,141 (4.3%) were treated at hospitals disproportionately serving the Hispanic community (Hispanic hospitals). After multivariate analysis, treatment in a Black hospital was associated with a 4% higher risk of mortality compared to treatment in a nonminority hospital (odds ratio, 1.04; 95% CI, 1.03-1.05; p less then 0.01). Treatment in a Hispanic hospital was associated with a 9% higher risk of mortality (odds ratio, 1.09; 95% CI, 1.07-1.11; p less then 0.01). Median hospital length of stay was almost 1 day longer at each of the disproportionately minority hospitals (nonminority hospitals 5.9 d; interquartile range, 3.1-11.0 d vs Hispanic 6.9 d; interquartile range, 3.6-12.9 d and Black 6.7 d, interquartile range, 3.4-13.2 d; both p less then 0.01). CONCLUSIONS Patients with sepsis regardless of race who were treated in disproportionately high minority hospitals suffered significa

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