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https://www.selleckchem.com/products/az628.html Breathlessness, aches and pains, abdominal discomfort and hoarse voice! These may sound like the clinical presentation of COVID‐19, but Nay! These are the symptoms experienced by the countless health professions education (HPE) teachers who have suddenly been thrust into the online world to engage learners.Leaf photosynthetic properties, e.g., the maximum carboxylation velocity or Vc ,max , change with leaf age due to ontogenetic processes. This study introduces an optimal dynamic allocation scheme to model changes in leaf-level photosynthetic capacity as function of leaf biochemical constraints (costs of synthesis and defense), nitrogen availability and other environmental factors (e.g., light). ▪The model consists of a system of equations describing RuBisCO synthesis and degradation within chloroplasts, defense and aging at leaf levels, nitrogen transfer and carbon budget at plant levels. ▪Model results show that optimal allocation principles explained RuBisCO dynamics with leaf age. An approximated analytical solution can reproduce the basic pattern of RuBisCO and Vc ,max in rice and in two tropical tree species. The model also reveals leaf life complementarities that remained unexplained in previous approaches, as the interplay between Vc ,max at maturation, life span, and the decline in photosynthetic capacity with age. Furthermore, it explores the role of defense, which is not implemented in current models. ▪This framework covers some of the existing gaps in integrating multiple processes across plant organs (chloroplast, leaf and whole plant) and it is a first-step into representing mechanistically leaf ontogenetic processes into physiological and ecosystem models.Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic inflammatory disorder of the pilosebaceous units. To date, studies on the risk of keratinocyte carcinoma (KC), defined as basal cell carcinoma (BCC) and squamous cell carcinoma (SC

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