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https://www.selleckchem.com/pharmacological_epigenetics.html Differences in feature values between time points were calculated for each feature, and logistic regression was used in conjunction with analysis of variance to classify patients with and without RP ( p 0.5 . Conclusions Radiomics features extracted using different software packages can result in differences in classification ability. © 2020 Society of Photo-Optical Instrumentation Engineers (SPIE).Purpose Placental size in early pregnancy has been associated with important clinical outcomes, including fetal growth. However, extraction of placental size from three-dimensional ultrasound (3DUS) requires time-consuming interactive segmentation methods and is prone to user variability. We propose a semiautomated segmentation technique that requires minimal user input to robustly measure placental volume from 3DUS images. Approach For semiautomated segmentation, a single, central 2D slice was manually annotated to initialize an automated multi-atlas label fusion (MALF) algorithm. The dataset consisted of 47 3DUS volumes obtained at 11 to 14 weeks in singleton pregnancies (28 anterior and 19 posterior). Twenty-six of these subjects were imaged twice within the same session. Dice overlap and surface distance were used to quantify the automated segmentation accuracy compared to expert manual segmentations. The mean placental volume measurements obtained by our method and VOCAL (virtual organ computer-aided analysis), a leading commercial semiautomated method, were compared to the manual reference set. The test-retest reliability was also assessed. Results The overlap between our automated segmentation and manual (mean Dice 0.824 ± 0.061 , median 0.831) was within the range reported by other methods requiring extensive manual input. The average surface distance was 1.66 ± 0.96    mm . The correlation coefficient between test-retest volumes was r = 0.88 , and the intraclass correlation was ICC ( 1 ) = 0.86 . Conclu

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