Aerobic performance is considered an important determinant of match running performance in soccer, but studies have rarely investigated this issue in top-level players. This study examined the possible associations between direct measures of aerobic performance and match running performance in elite soccer players. Aerobic performance was tested at the beginning of the season in laboratory settings. The match-running performance was measured by a global positioning system over a competitive half-season for a total of 82 match performances in professional players from Croatia (age 23.76 ± 2.64; body height 181.62 ± 7.09 cm; body mass 77.01 ± 6.34 kg) and clustered as central player (n = 57) and side player (n = 25) performance. No significant differences in aerobic performance were noted between central and side players. The anaerobic threshold was correlated with high-speed running (19.8-25.1 km/h), sprint running (>25.1 km/h), and high-intensity running (>19.8 km/h) among side players (r = 0.52, 0.53, and 0.59, respectively; p less then 0.01). For central players, the aerobic threshold was correlated with the total distance covered, low-intensity running ( less then 14.3 km/h), and distance covered in the zone of running (14.4-19.7 km/h) (r = 0.47, 0.49, and 0.39; p less then 0.01, 0.01, and 0.03, respectively). Conditioning for central players should include activities with intensities corresponding to aerobic thresholds, while conditioning of side players should be focused on the development of anaerobic thresholds.The cervical spine injury is a complicated procedure in the combination of different injury loads and postures. The aim of this study is to investigate the injury mechanism considering different types of cervical curvatures subjected to contusion loads. A finite element model of a cervical spinal cord was constructed. Gray matter, white matter and pia matter were modeled and hyperelastic material properties were assigned. Convergence analysis and validation analysis were carried out. The model was simulated in 3 different spinal curvatures and loaded by 2 directions with 4 compression degrees. The maximum von Mises stress in the whole model was concentrated in the pia matter in all loading cases. When investigating spinal cord injury, the pia matter must be considered. For all three curvatures, the stress in the gray matter and white matter was higher in front-to-back loading condition than that in back-to-front loading condition. The front-to-back impact may cause a larger damage. A back-to-front load damaged the structure around the central canal and a front-to-back contusion load damaged the anterior horn of the spinal cord at most time. From the view of the maximum stress, the lordotic curvature did not show significant buffering effect. However, the pathological curvature had large areas affected and the lordotic curvature showed some benefits to some degree from the view of stress distribution.Since its first emergence, people have been having different attitudes and perceptions towards the COVID-19 pandemic. Perceptions (e.g. perception of disease threat) have profound consequences on behavior (e.g medication adherence). If adequately available, perception studies guide public awareness efforts or help in understanding behavior. In this study , repeated cross-sectional data were collected from 376 randomly selected globally located respondents over two periods. Participants perceived COVID-19 as severe as Tumor and AIDS (F (2,722) = 2.347; p = .096), and as more severe than other 14 illnesses; e.g. Diabetes and High blood pressure. Age-wise, participants above 50 age group perceived COVID-19 as more severe than the under 50 (F (1,240) = 10.378, p less then .001). In addition, the magnitude of severity perception was found to be dependent on the different stages of the outbreak in the respondents' corresponding countries. In a gap of a month time, depression surpassed COVID-19 to be perceived as more severe. Majority of respondents attributed COVID-19 as a physical (vs mental) illness, thus considered it as more severe (vs less severe). Implications of this study could mean; (1) COVID-19 patients might be susceptible to social stigmatization as HIV patients, and (2) severity perception is shaping intervention friendly behaviors.This study aimed to understand the types and characteristics of lonely elderly from the perspective of social isolation and compare their differences in quality of life (QOL). A cross-sectional survey of 2148 lonely elderly in Shanxi province, China was conducted. The latent profile analysis was used to classify the lonely elderly and describe their characteristics. A hierarchical multilinear regression method was applied to evaluate their differences in QOL. The lonely elderly can be divided into two categories Class-Ⅰ, in low social isolation with a significant correlation between social isolation and loneliness (p 0.05). QOL of Class-Ⅰ was significantly higher than that of Class-Ⅱ. Class-Ⅱ was in a state of self-imposed isolation with poor QOL and should be the focus-group during practical intervention.The aim of this study was to assess the potential of the woody nickel hyperaccumulator species Blepharidium guatemalense (Standl.) Standl. for agromining in southeastern Mexico. Pot trials consisting of nickel dosing (0, 20, 50, 100, and 250 mg Ni kg-1), and synthetic and organic fertilization were conducted. Field trials were also undertaken with different harvesting regimes of B.  https://www.selleckchem.com/products/rmc-9805.html  guatemalense. Foliar nickel concentrations increased significantly with rising nickel additions, with a 300-fold increase at 250 mg Ni kg-1 treatment relative to the control. Synthetic fertilization strongly increased nickel uptake without any change in plant growth or biomass, whereas organic fertilization enhanced plant shoot biomass with a negligible effect on foliar nickel concentrations. A 5-year-old stand which was subsequently harvested twice per year produced the maximum nickel yield tree-1 yr-1, with an estimated total nickel yield of 142 kg ha-1 yr-1. Blepharidium guatemalense is a prime candidate for nickel agromining on account of its high foliar Ni concentrations, high bioconcentration (180) and translocation factors (3.