The peripancreatic HMO with severe fibrosis can occur duodenal stenosis, and it is mimicking periampullary cancer. However, the preoperative diagnosis of spontaneous HMO is difficult, and a diagnosis confirmed after surgery. Herein, we described our experience of managing a rare case of duodenal stenosis due to spontaneous HMO involving peripancreatic tissue. Herein, we described our experience of managing a rare case of duodenal stenosis due to spontaneous HMO involving peripancreatic tissue. Carcinosarcoma is an extremely rare subtype of gallbladder cancer with a worldwide prevalence of less than 1%. Carcinosarcomas are composed of a mixture of epithelial and mesenchymal components. Preoperative diagnosis of carcinosarcoma is challenging considering the non-specific clinical presentation and radiological findings. A 63 years old female presented with right hypochondrium abdominal pain for 6 months. CA 19.9 level was high. Computed tomography of abdomen showed gallstones with enhancing wall thickening, along with enlarged portacaval lymph node. Endoscopic ultrasound-guided biopsy of porta hepatis lymph node was done which showed moderately differentiated adenocarcinoma. Hence, she underwent extended cholecystectomy with extended porta hepatis lymph node dissection. Final histopathological result showed carcinosarcoma (pT2a, pN1 M0). Unfortunately, she passed away 7 months post-operatively. The majority of patients with carcinosarcomas are asymptomatic but can develop unspecific symptoms in atherapy and which patients would benefit the most from surgery. The laparoscopic approach is a very popular technique for many gastrointestinal operations and barbed sutures may improve the difficulties of intracorporeal anastomosis by eliminating the need for knot tying. The aim of this systematic review with a meta-analysis is to explore literature to establish the security profile of barbed suture compared with conventional laparoscopic sutures. A systematic search was performed in all electronic databases (PubMed, Web of Science, Scopus, EMBASE) and 12 studies were included in the analysis, involving 27,133 patients, whereof 3372 cases (patients undergone barbed suture usage) and 23,761 controls (patients undergone conventional suture usage). We found 3 studies discussing differences between barbed and conventional sutures in colorectal surgery and 8 studies presenting results in bariatric surgery, both in Roux-en-y gastric bypass and Mini Gastric/One Anastomosis Gastric Bypass. We found comparable rate of leaks, bleedings and stenosis. The meta-regression analysis demonstrated that, both in case of bariatric and colorectal surgery, the demographic characteristic of patients and the oncological features of neoplasms did not impact of these findings. As expected, operative time is significantly shorter when barbed suture is used. Our analysis on current literature define an acceptable security profile for barbed suture with effective results particularly in terms of shorter operative time. Our analysis on current literature define an acceptable security profile for barbed suture with effective results particularly in terms of shorter operative time. The present systematic review investigated return to sport, patient reported outcome measures (PROMs), complications and subsequent progression to total hip arthroplasty (THA) in patients undergoing arthroscopic labral repair for FAI. Following the PRISMA statement, the literature search was performed in February 2021. The outcomes of interest were rate of return to sport, modified Harris Hip Score (mHHS), the subscales Activities of Daily Living and Sport-Specific Subscale of the Hip Outcome Score (HOS-ADL and HOS-SSS, respectively). Complications, revision surgeries and progression to total hip arthroplasty were recorded. Data from 210 procedures were retrieved. The mean follow-up was 34.0 (24.0-42.5) months. https://www.selleckchem.com/products/OSI-930.html The mean age of the patients was 32.0 (20.0-47.0) years, while the mean BMI was 20.9 (20.1-21.7) kg/m . 52.8% (111 of 210 patients) were women. At 24-month follow-up, 100% of the patients had returned to sport. At a mean of 34 months follow-up, the mean mHHS increased by 25.5% (P=0.02), the mean HOS-ADL by 23.0% (P=0.03), the mean HOS-SSS by 32.8% (P=0.001). No complications were observed. The rate of revision was 4.3% (9 of 210 procedures). At a mean of 37.9±7.5 months, 1.9% of patients (4/210) underwent THA. Arthroscopic labral refixation for FAI yields reliably positive clinical outcomes, with a low rate of revision and conversion to THA. Arthroscopic labral refixation for FAI yields reliably positive clinical outcomes, with a low rate of revision and conversion to THA. This case report describes a patient with severe iatrogenic dental biprotrusion who visited for a second assessment. The patient presented first premolar maxillary extractions, resorbed maxillary incisors and dehiscences in the anterior buccal and palatal cortical bone diagnosed with cone-beam computed tomography (CBCT). At the beginning of treatment, fixed appliances were bonded on all teeth except on the upper incisors to prevent further root resorption. Mandibular first premolar extractions, miniscrews and corticotomies were scheduled for gaining distalization of the teeth in the four quadrants. When this was achieved, an occlusal splint was placed to extrude the posterior teeth with interarch elastics for increasing the vertical dimension. Next, brackets were placed on the maxillary incisors and a comprehensive orthodontic treatment was performed. After treatment, changes in incisor positioning were evident, varying the interincisal angle by 57.6 degrees. Nevertheless, slight root resorption of the upper incisors was observed. Correct diagnosis is necessary to design an adequate treatment plan and make orthodontists aware of possible severe unwanted tooth movements before they occur. In dental biprotrusion without overjet, the first objective should be to distalize mandibular teeth prior to maxillary teeth retraction. Correct diagnosis is necessary to design an adequate treatment plan and make orthodontists aware of possible severe unwanted tooth movements before they occur. In dental biprotrusion without overjet, the first objective should be to distalize mandibular teeth prior to maxillary teeth retraction.