https://www.selleckchem.com/products/vtp50469.html Asthma is a common pediatric chronic respiratory disease worldwide. Previous studies showed the prevalence of childhood asthma increased in developed countries as well as in Taiwan in the late 20th century. Recently, several reports from different parts of the world showed a reversed trend in this epidemic of childhood asthma prevalence. This study investigated the trend of childhood asthma through serial cross-section questionnaire surveys in the southern part of Taiwan, and identified associated factors related to this trend in elementary school children. We used the Chinese version of the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire to assess the asthma status of elementary school students aged 6-12 years in Tainan city in 3 independent study periods, namely, 2008-2009, 2010-2012, and 2017-2018. We assessed the trend of "asthma" and "related respiratory symptoms" across 3 study periods. Of the 19,633 respondents, 17,545 (89.4%) completed the questionnaires. After an seem to be related to this decreasing trend of asthma in school children. Our findings will provide the scientific base to empower prevention policy to reverse the trend of childhood asthma prevalence. N/A. N/A. Azole resistance in spp. is becoming a public health problem worldwide. However, data about this subject is lacking in Latin American countries. This review focuses in the epidemiology and molecular mechanisms of azole resistance in spp. emphasizing in Latin America. Data on stands out because it is the most prevalent spp. pathogen. Azole resistance in spp. emergence was linked with intensive use of these antifungals both in the clinical setting and in the environment (as pesticides). Reports on azole-resistant strains are being constantly published in different countries. Molecular mechanisms of resistance mainly involve substitution in the azole target ( ) and/or overexpression of this gene. However, several