One of the challenges today is to face fake news (false information) in health due to its potential impact on people's lives. This article contributes to a new application of social impact in social media (SISM) methodology. This study focuses on the social impact of the research to identify what type of health information is false and what type of information is evidence of the social impact shared in social media. The analysis of social media includes Reddit, Facebook, and Twitter. This analysis contributes to identifying how interactions in these forms of social media depend on the type of information shared. The results indicate that messages focused on fake health information are mostly aggressive, those based on evidence of social impact are respectful and transformative, and finally, deliberation contexts promoted in social media overcome false information about health. These results contribute to advancing knowledge in overcoming fake health-related news shared in social media.People with neurological disorders suffer from poor mobility, poor balance, fatigue, isolation and monotonous everyday activities. Studies show that equine-assisted interventions can improve their mobility and balance, but could these kinds of interventions also increase participants' activity repertoire and self-assessed health, and reduce their fatigue? The study was conducted as a prospective, controlled study with three cohorts followed for one year intervention group (n = 14), control group Passive (n = 29), and control group Active (n = 147). Participants in the study were affected by neurological disease or injury that limited their opportunities for an active everyday life. The intervention group lacked regular activities outside the home before the intervention, which consisted of riding once a week, led by a certified therapist. Control group Passive lacked regular activities outside the home, while control group Active had several activities outside the home per week. Primary outcome measures were activity repertoire measured with Occupational Value Assessment questionnaire. Secondary outcome measures were global self-assessed health measured with EuroQol-VAS and fatigue measured with Shirom-Melamed Burnout Questionnaire. The intervention group's activity repertoire and self-assessed health increased significantly compared to both baseline and the control groups. Equine-assisted interventions could help to improve the perceived value of everyday occupations and quality of life, as well as break isolation and increase the activity repertoire of people with neurological disorders.Photoresponsive polymers have attracted increasing interest for a variety of applications. Here, we report a family of photoresponsive polypeptoid-based copolymer poly(ethylene glycol)-b-poly(N-(S-(o-nitrobenzyl)-thioethyl) glycine)-co-poly(N-(2-phenylethyl) glycine) (PEG-b-PNSN-co-PNPE) synthesized by the controlled ring-opening polymerization (ROP) technique. The key feature of the design is to incorporate both o-nitrobenzyl group moiety to offer the photoresponsive property and phenethyl residues to tune the structural and amphiphilic property of the system. We demonstrate that the cleavage degree of the o-nitrobenzyl group can reach to 100% upon UV-irradiation. With delicate design, a photoresponsive vesicle-to-sphere transition has been observed that facilitates the release of the encapsulants. This work provides a facile approach to prepare a type of photoresponsive polymers with tunable properties for drug delivery.Microencapsulated peppermint (Mentha x piperita L.) essential oil (MPEO) is a prospective botanical herbicide. A hypothesis was formulated, that the type of growth medium (vermiculite or silty clay loam soil substrate) affects the phytotoxic potential of MPEO. A pot experiment in a randomized design assessed the effect of five doses of MPEO in a range of 0-108 g m-2 or 0-145 g m-2, mixed with vermiculite or with soil, respectively, on early growth of white mustard (Sinapis alba L. cv. Zlata), tested here as a model "weed" species. The morphologic analyses were supported by selected biochemical measurements. The two highest doses of microcapsules (from 73 to 145 g m-2) caused a significant decrease of plants' height and biomass. An increase of anthocyanin content in the aboveground parts of mustard is supportive for the induction of defense mechanisms against MPEO-triggered stress in mustard leaves. In conclusion, MPEO appears as a promising bio-herbicide. However, we are aware that further studies on the mechanisms of action of MPEO in different weed species are necessary to test (i) whether or not the effect is consistent to be proficiently exploited for weed control in field and (ii) to deepen the biochemical and physiological reactions by the plants against MPEO treatments.Background and objectives It is unclear why many patients with hypothyroidism prefer the use of desiccated thyroid extract (DTE) as a thyroid hormone replacement formulation over levothyroxine (LT4) treatment, as recommended by clinical practice guidelines. We analyzed patient-reported information from patient online forums to better understand patient preferences for and attitudes toward the use of DTE to treat hypothyroidism. Materials and Methods We conducted a mixed-methods study by evaluating the content of online posts from three popular hypothyroidism forums from patients currently taking DTE (n = 673). From these posts, we extracted descriptive information on patient demographics and clinical characteristics and qualitatively analyzed posts' content to explore patient perceptions on DTE and other therapies further.  https://www.selleckchem.com/  Results Nearly half (46%) of the patients reported that a clinician initially drove their interest in trying DTE. Patients described many reasons for switching from a previous therapeutic averall well-being, despite the risks associated with DTE.An analytical and cold model study of a prototype extended vane rod-type RFQ (radio frequency quadrupole linac) is presented. The bead-pull measurement allowed us to experimentally determine the effect of shaping of the vane-supporting posts and, most interestingly, the size of the vacuum enclosure in the dipolar and quadrupolar field asymmetry. Disk shaped beads of BaTiO3 have been tailor made for this purpose. The special shape of the beads has allowed precise measurements of frequency shifts all along the length of the RFQ. The measured quadrupolar asymmetry and dipole component at a radial distance of 7 mm from the beam axis are within ±1% for the optimized structure. Particle tracking of a 10 mA proton beam with a simulated 3D field for the optimized full scale RFQ with modulated vanes has been carried out. Simulation shows vertical and horizontal shifts of only 0.01 mm and 0.03 mm, respectively, for the accelerated beam at the exit of RFQ. The percentage of accelerated particles lying within an energy width of ±40 keV about 800 keV is increased from 86% for the original enclosure to 88% for the reduced enclosure, whereas the transmission efficiency is 100% for both the cases.