A series of new chemosensor molecules bearing benzothiazole-, quinoline- and phthalazine-functionalized fluorene derivatives were synthesized and their complexation behaviors with Fe3+ and Sn2+ ions were investigated. The sensing abilities of their complexes towards both cyanide and sulfide anions were investigated by colorimetric and fluorometric techniques in detail. The sensing mechanism was investigated by Job's and Scatchard plots evaluations, and also absorption/fluorescence titration experiments. Among the studied dye/metal binary systems, F-BT sensor to Fe3+ giving the detection limits of 3.1 µg has also displayed high selectivity and sensitivity towards CN- and S2- anions, lead to a significant color change of the solution observable by the naked eye. Asthma has been a global problem, especially in children. We aim to evaluate the contemporary prevalence and influencing factors of asthma among children aged 3-7years in Shanghai, China. A random sample of preschool children was included in this study. The International Study of Asthma and Allergies in Childhood questionnaire was adopted to assess the childhood asthma. https://www.selleckchem.com/peptide/box5.html Multivariable logistic regression models were used to evaluate the associations between independent variables and childhood asthma. Of 6389 preschool children who were invited to take part in this study, 6163 (response rate 96.5%) completed the questionnaire and were included in the analysis. The overall prevalence of asthma was 14.6% which increased more than six folds from 2.1% in 1990. Being male, younger age, preterm delivery, beingborn in spring or autumn, beingdelivered by elective cesarean section without indication, miscarriage, high socioeconomic status, having allergy history, and exposure to passive smoking, latex paint, and dust were potential risk factors for childhood asthma. Spending more time outdoors (> 30min/day), having indoor plants, and cleaning rooms more frequently were potential protective factors. The prevalence of childhood asthma in Shanghai has increased dramatically during the past three decades. The findings about risk and protective factors of childhood asthma could be used to develop appropriate strategies to prevent and control childhood asthma in Shanghai and in other similar metropolitan cities. The prevalence of childhood asthma in Shanghai has increased dramatically during the past three decades. The findings about risk and protective factors of childhood asthma could be used to develop appropriate strategies to prevent and control childhood asthma in Shanghai and in other similar metropolitan cities. Echinococcosis is a common health problem in the Mediterranean and the Middle East, and manifests without any symptoms, even in the advanced stages. The present study aimed to investigate the cell mediated-immunoregulatory milieu in rats' echinococcosis induced by three different viability status of Echinococcus granulosus especially in the semi-calcareous stage, which can be used as novel biomarkers to monitor disease progression and open the door to a deeper understanding of the pathways that could contribute to complementary echinococcosis therapies. Rat infection with echinococcosis was induced by three different viable statuses of Echinococcus granulosus (G6) camel strain. During the different stages of parasitic infection, blood serum was harvested from rats containing low-, high-, and not viable (not completely transformed to the calcareous status) protoscoleces fluid. The host Th1/Th2 cytokines-mediated immune cell activation, as well as CD3/TCRE immunoregulation, and proliferation responses weri-calcareous stage causes a severe immunological response. Alcohol is the most misused substance in the world. For people living with HIV (PLWH), alcohol misuse may impact ART adherence and viral suppression. This review of the most recently published alcohol intervention studies with PLWH examines how these studies considered gender in the samples, design, and analyses. Three searches were conducted initially, and 13 intervention studies fit our criteria with alcohol outcomes. In general, most studies did not consider gender and had used small samples, and few demonstrated significant efficacy/effectiveness outcomes. Five studies considered gender in their samples or analyses and/or were woman-focused with larger samples and demonstrated significant outcomes. It is essential for women who misuse alcohol to not only be well represented in alcohol and HIV research but also for studies to consider the barriers to reaching them and their contextual demands and/or co-occurring issues that may affect participation and outcomes in intervention research. Three searches were conducted initially, and 13 intervention studies fit our criteria with alcohol outcomes. In general, most studies did not consider gender and had used small samples, and few demonstrated significant efficacy/effectiveness outcomes. Five studies considered gender in their samples or analyses and/or were woman-focused with larger samples and demonstrated significant outcomes. It is essential for women who misuse alcohol to not only be well represented in alcohol and HIV research but also for studies to consider the barriers to reaching them and their contextual demands and/or co-occurring issues that may affect participation and outcomes in intervention research.Toxic metals and particle pollutants in urbanized cities have significantly increased over the past few decades mainly due to rapid urbanization and unplanned infrastructure. This research aimed at estimating the concentration of toxic metals and particle pollutants and the associated risks to public health across different land-use settings including commercial area (CA), urban area (UA), residential area (RA), and industrial area (IA). A total of 47 samples for both soil and air were collected from different land-use settings of Faisalabad city in Pakistan. Mean concentrations of toxic metals such as Mn, Zn, Pb, Ni, Cr, Co, and Cd in all land-use settings were 92.68, 4.06, 1.34, 0.16, 0.07, 0.03, and 0.02 mg kg-1, respectively. Mean values of PM10, PM2.5, and Mn in all land-use settings were found 5.14, 1.34, and 1.9 times higher than the World Health Organization (WHO) guidelines. Mn was found as the most hazardous metal in terms of pollution load index (PLI) and contamination factor (CF) in the studied area.