https://www.selleckchem.com/products/nd-630.html 05). A significant or quasi-significant increase (P = .068 and .047 for CPT and RPT, respectively) in bone mineral content was observed after both interventions. A significant reduction in fat mass (P = .017), along with a trend (P = .059) toward a reduced body mass, was observed after RPT, but not CPT (P = .076 for the group × time interaction effect). Significant benefits (P < .05) were also observed for most strength-related outcomes after RPT, but not CPT. CPT and RPT are both effective strategies for the improvement of endurance performance and bone health in professional cyclists, although the latter tends to result in greater improvements in body composition and muscle strength/power. CPT and RPT are both effective strategies for the improvement of endurance performance and bone health in professional cyclists, although the latter tends to result in greater improvements in body composition and muscle strength/power. The authors investigated the effect of foot cooling (FC) between sets in a leg press pyramid workout with resistance-trained participants. A total of 12 resistance-trained men (age = 21.8 [0.6]y; training experience = 1.7 [1]y) performed a pyramid workout, including 4 sets of 85% to 90% 1-repetition maximum leg press exercise to exhaustion with interset FC or noncooling in a repeated-measures crossover design separated by 5days. The authors immersed the participants' feet in 10°C water for 2.5minutes between sets. Two-way repeated-measures analysis of variance revealed that FC elicited significantly higher repetitions and electromyography (EMG) values of the vastus lateralis (simple main effect of condition) than did noncooling (P < .05) in the second (repetitions 11 [3.5] vs 7.75 [3.2]; EMG 63.4% [19.4%] vs 54.5% [18.4%]), third (repetitions 8.9 [3.2] vs 6.4 [2.1]; EMG 71.5% [17.4%] vs 60.6% [19.4%]), and fourth (repetitions 7.5 [2.7] vs 5.1 [2.2]; EMG 75.2% [19.6%] vs 59.3% [23.5%]) sets. The auth