https://www.selleckchem.com/products/hoipin-8.html Assessment of cytotoxicity showed that etoposide nanoparticles with PGA85%C18 were more potent than an equivalent amount of free drug. This screening method to match polymers to drugs to monitor based drug and polymer interactions thus resulted in the formulation of nanoparticles with higher drug loading and slower release and potential for further development for clinical applications.Understanding water wetting layers on solid surfaces is essential for many natural and industrial processes. Here we find a helical ice monolayer with every six water molecules helically arranged along the normal of the basal plane by performing an intensive structural search based on ab initio calculations. The helical ice is more stable than all previous models of monolayer and bilayer ices in a wide range of water densities both in vacuum and on weakly interacting substrates due to a stronger network of hydrogen bonds enabled by the helical geometry. More compelling is the fact that this model adequately explains a recent experimental ice monolayer grown on graphite in terms of the lattice parameter, water density, and Moiré pattern. The helical character in the new ice model echoes previously reported helical motifs in one-dimensional ice structures and suggests an unexpected capability of hydrogen bonds in driving the surface reconstruction of ice structures.A simple and straightforward approach to synthesize oil-in-water (O/W) emulsions under high salinity and temperature using zwitterion-functionalized latexes are presented in this work. First, well-defined functionalized latexes were synthesized by emulsifier-free emulsion copolymerization in the presence of precursor sulfobetaine comonomer using brine as a continuous phase. The surface-functionalized latex particles were then characterized by DLS, SEM, TEM, XPS, and TGA. The functionalized latex exhibited antipolyelectrolyte behavior in high salinity brine and at high tempera