Fully understanding of multistate quantum systems could become formidable if not impossible as the system dimensionality increases. One ideal strategy to comprehend complex systems is to transform the system representation into a more structural one so that major characteristics, connections, and even underlying mechanisms can stand out from the huge unstructured information, e.g., the construction of spin eigenfunctions for a system of multiple spins through the diagonalization of the system Hamiltonian matrix. Here, instead of direct matrix diagonalization, the recently developed modular tensor diagram approach is applied to reorganize the state space structure of multispin systems, extending previous investigations on exciton pair states to exciton trimer states. This implementation demonstrates that the proposed approach not only provides a systematical way to transform the high dimensional multistate system into a well organized structure based on basic (exciton) modules but also paves the way to further analysis on potential applications. For example, the analysis on the state space of the exciton trimer system suggests a possible scheme to improve the laser performance via single fission involving multiexcitations and/or multiple fission steps.
  The aims of this study were 1) to investigate the impacts that an eccentric overload training (EOT) and a small-side game training (SSGT) have on the characteristics of the accelerations (ACC) and decelerations (DCC) of the players in a soccer match; and 2) to determine if EOT and SSGT could affect the ACC and DCC reduction over time in a soccer match.
 
  Twenty-three female soccer players from a Spanish professional club were split into three groups a small-sided game training group (SGG), an eccentric overload training group (EOG) and a control group (CG).
 
  The SSG improved the high intensity distance performed (ES [CI]=0.72 [0.22; 1.22]), the number of high intensity actions (ES [CI]=0.65 [0.01; 1.29]), the percentage of repeated high intensity actions (ES [CI]=0.54 [-0.17; 1.25]), the initial velocity of the ACC (ES [CI]=0.55 [-0.08; 1.17]) and the percentage of repeated accelerations (ES [CI]=0.87 [-0.18; 1.91]) with respect to the control group. The EOG obtained better results in distance travelling accelerating (ES [CI]=0.84 [0.09; 1.60]) and decelerating (ES [CI]=0.87 [0.23; 1.51]) above 3 m/s
  , maximum ACC (ES [CI]=1.92 [0.90; 2.94]) and DCC (ES [CI]=1.29 [0.44; 2.14]) and the average of maximum ACC (ES [CI]=0.89 [0.23; 1.54]) and DCC (ES [CI]=1.08 [0.62; 1.55]) with respect to the CG. A decrement in the ACC and DCC performance was observed between the first and last 15 minutes of the competition, except for the EOG.
 
  The SSG obtained mainly improvements in variables related with efforts repetitions and the capacity of maintaining the ACC and the DCC over time, while improvements in the EOG were related to intensity in the ACC and DCC.
 The SSG obtained mainly improvements in variables related with efforts repetitions and the capacity of maintaining the ACC and the DCC over time, while improvements in the EOG were related to intensity in the ACC and DCC.The International Society of Burn Injury (ISBI) published the second part of the ISBI practice guidelines for burn care in 2018 in the journal of Burns. The main content of the guideline includes first aid for burns, topical drugs, burn infection, management of arteriovenous catheterization and metabolism, exercise and functional training, pain management, sedation, blood transfusion, deep venous thrombosis, mental disorder, and outpatient and discharge management. This article was written with the purpose to interpret the main points of the practice guidelines.Exosomes are a kind of membrane vesicle with a diameter of 30-150 nm. It is formed by the budding of multiple vesicles in cells, which can fuse with the cell membrane and be released into the extracellular matrix. Adipose derived stem cells (ADSCs) have the potential of self-renewal and multi-directional differentiation. They can transport the active substance, regulate the inflammatory response, cell migration, proliferation, differentiation and angiogenesis via the action of paracrine exosomes, so as to enhance the ability of wound repair, promote wound healing, and inhibit the formation of scars. Chronic wounds refer to the wounds that can not reach the anatomic and functional integrity through the normal, orderly, and timely repair process, and the course of the wound healing is more than 4 weeks. At present, there are various treatment methods for chronic wounds, among which ADSCs, although showing a good application prospect, have some limitations due to ethical issues, while exosomes can avoid this problem. This article reviews the treatment of chronic wounds with ADSC exosomes.Objective To explore the clinical effects of anterograde sural neurovascular flap in repairing skin and soft tissue defect around the knee. Methods Nine patients with skin and soft tissue defect around the knee admitted to Beijing Fengtai YouAnMen Hospital from May 2011 to December 2018, were included in this retrospective descriptive study, including 8 males and 1 female, aged 16 to 65 years. The wound area after debridement ranged from 8 cm×5 cm to 18 cm×10 cm. Anterograde sural neurovascular flap was used to repair the wounds in 9 patients, with the area ranging from 9 cm×6 cm to 20 cm×12 cm. The donor sits of flaps in 2 patients were closed and sutured directly, and the donor sits of flaps in 7 patients were repaired with medial split-thickness skin graft of the ipsilateral thigh.  https://www.selleckchem.com/products/liraglutide.html  The flap survival, complications, and follow-up after operation were recorded. Results The flaps survived and the blood supply was good in 8 patients and the wounds were closed. One patient developed skin ischemic necrosis which was cured after three weeks of dressing change. All the skin grafts in the donor site of flap in 7 patients survived. In 6 months to 5 years of follow-up after surgery, the skin flap had good texture, color, and shape, and normal sensation. Except for one patient whose knee had poor recovery of function, the knee joint function of the other patients recovered well. Conclusions The anterograde sural neurovascular flap has the advantages of high survival rate, satisfactory appearance and functional recovery post surgery, and is an ideal flap for repairing the skin and soft tissue defect around the knee.