The goals of this review are (1) to describe the evidence behind the use of ceramic﻿s vs composite resin to restore teeth with anterior veneers using a minimally-invasive strategy; and (2) to discuss the choice of materials and techniques for anterior veneer restorations.
 
  In recent years new adhesive restorative materials and techniques have been introduced in dentistry, including nanofilled composite resins for direct restorations, new ceramic materials that combine esthetics and strength, and polymer/ceramic materials for indirect restorations that are fabricated chairside using CAD/CAM technology, allowing the dentist to design, mill, and cement the restoration in one session. In spite of the novelty and new technology behind the introduction of new materials, the available evidence that backs some of these materials does not justify their use over similar materials or techniques that have been used by dentists for some years. Notwithstanding the success of laminate veneers and the popularity of new ma save tooth structure, and promote the well-being of our patients. The armamentarium of new dental materials for esthetic clinical procedures has increased exponentially in the last few years. The use of different materials and techniques for anterior veneer restorations must be based on sound evidence rather than on the marketing hype or testimonials.
 The ultimate goals of any restorative treatment are to restore function and esthetics, prevent recurrent caries lesions and bacterial leakage into the pulp space, save tooth structure, and promote the well-being of our patients. The armamentarium of new dental materials for esthetic clinical procedures has increased exponentially in the last few years. The use of different materials and techniques for anterior veneer restorations must be based on sound evidence rather than on the marketing hype or testimonials.
  The use of electrocardiography (ECG) is a practical method to evaluate the response to cardiac resynchronization therapy (CRT) implantation, as it is easily performed and saves time.
 
  This study aimed to assess the predictive value of the T-wave duration and Tpeak-Tend (Tp-e) interval following the CRT implantation administered to heart failure patients.
 
  Sixty-seven patients with left ventricular ejection fraction ≤35, New York Heart Association (NYHA) class II-III, ambulatory class IV, normal sinus rhythm, who have complete left bundle branch block on ECG and treated with CRT were included in this study. Patients who have manifested a ≥10% improvement in ejection fraction following CRT implantation, were categorized as "responders", and the remaining patients were categorized as "non-responders". ECGs and echocardiograms were evaluated both six months before and after CRT implantation.
 
  The post-CRT QRS duration (P = 0.01), cQT interval (P = 0.005), T-wave (P &lt;0.001), and Tp-e interval (P &lt;0.001) were found to be significantly reduced in the responder group compared to the non-responder group. The receiver operating characteristics curve analyses revealed that the predictive optimal cut-off of the T-wave was &lt;182 ms (P &lt;0.001), and that of the Tp-e interval was &lt;92 ms (P &lt;0.001).
 
  T-wave and Tp-e interval may be independent predictors of a favorable CRT response in heart failure patients.
 T-wave and Tp-e interval may be independent predictors of a favorable CRT response in heart failure patients.
  Neuron-specific enolase (NSE) is a biomarker for neurological outcomes after cardiac arrest with the most evidence collected thus far; however, recommended prognostic cutoff values are lacking owing to the discrepancies in the published data.
 
  To establish NSE cutoff values for prognostication in the environment of a cardiac intensive care unit following out-of-hospital cardiac arrest (OHCA).
 
  A consecutive series of 82 patients admitted after OHCA were enrolled. Blood samples for the measurement of NSE levels were collected at admission and after 1, 3, 12, 24, 48, and 72 h. Neurological outcomes were quantified using the cerebral performance category (CPC) index. Each patient was classified into either the good (CPC ≤ 2) or poor prognosis (CPC ≥ 3) group.
 
  Median NSE concentrations were higher in the poor prognosis group, and the difference reached significance at 48 and 74 h (84.4 ng/ml versus 22.9 ng/ml at 48 h and 152.1 ng/ml versus 18.7 ng/ml at 72 h, P &lt; 0.001). Moreover, in the poor prognosis group, NSE increased significantly between 24 and 72 h (P &lt; 0.001).  https://www.selleckchem.com/products/bms309403.html  NSE cutoffs for the prediction of poor prognosis after OHCA were 39.8 ng/ml, 78.7 ng/ml and 46.2 ng/ml for 24, 48, and 72 h, respectively. The areas under the curve were significant at each time point, with the highest values at 48 and 72 h after admission (0.849 and 0.964, respectively).
 
  Elevated NSE concentrations with a rise in levels in serial measurements may be utilized in the prognostication algorithm after OHCA.
 Elevated NSE concentrations with a rise in levels in serial measurements may be utilized in the prognostication algorithm after OHCA.
  The long-term impact of extreme prematurity on cardiac structure and function has not been fully evaluated.
 
  To assess cardiac condition at 11 years of age in a local cohort of extremely low birth weight (ELBW) children born between 2002 and 2004 and compare it to a previous study in the same group at 7 years of age.
 
  Sixty-four children with ELBW (median birth weight 890 g) and 36 children born at full term underwent echocardiography and physical examination.
 
  M-mode echocardiography parameters, expressed as z-scores for body surface area (mean (SD)), showed significant differences in left ventricle end-diastolic dimension (-1.01 (0.91) vs. 0.35 (0.71); P &lt; 0.001), left ventricle end-systolic dimension (-0.29 (0.92) vs. 0.57 (0.65); P &lt; 0.001), aorta dimension (0.63 (1.14) vs. 1.63 (1.30); P &lt; 0.001), and left atrial dimension (-1.75 (0.97) vs. -0.01 (0.86); P &lt; 0.001) between the study group and controls at 11 years of age. Fractional shortening (FS) and ejection fraction (EF) were higher in the ELBW children than in their full-term counterparts (33.6 (5.5) vs. 30.8 (4.34); P = 0.009 and 0.63 (0.07) vs. 0.58 (0.06); P = 0.005, respectively) at a mean age of 11 years.
 
  The ELBW children had smaller hearts than full-term controls at both 7 and 11 years of age. The FS and EF were elevated in the group of 11-year-old ELBW children. We observed comparable progress in cardiac growth (approximately 20%) in premature and full-term children over a 4-year study period.
 The ELBW children had smaller hearts than full-term controls at both 7 and 11 years of age. The FS and EF were elevated in the group of 11-year-old ELBW children. We observed comparable progress in cardiac growth (approximately 20%) in premature and full-term children over a 4-year study period.