The study found no evidence that S-STOP reduced the prevalence of alcohol sales to apparently impaired patrons during the two intervention stages of the study.
 
  The findings highlight the need for developing effective interventions to prevent overservice and should prompt college and university leaders to take the lead in addressing the problem of alcohol overservice at on-premises establishments by working with community leaders, law enforcement, and retailers.
 The findings highlight the need for developing effective interventions to prevent overservice and should prompt college and university leaders to take the lead in addressing the problem of alcohol overservice at on-premises establishments by working with community leaders, law enforcement, and retailers.Although previous research has identified that perfectionism is associated with both narcissism and workaholism, research into the specific roles of potential perfectionism classes in these personality dynamics is currently unavailable. Furthermore, no study has investigated if the "useless superiority effort" dimension of inferiority feelings, which indicates an increased need for superiority over others potentially to overcome self-perceived inferiorities, is related to other important personality dynamics. This study was therefore conducted to identify if potential perfectionism classes that exist among academicians (N = 317) can simultaneously explain significant differences in their tendencies toward workaholism, narcissism, and useless superiority effort, after controlling for potential social desirability effect. A latent class analysis of two dimensions of perfectionism (discrepancy and high standards) revealed four distinct classes of academicians; non-perfectionists (NONPs; 20%), maladaptive perfectionists (MPs; 17%), normal perfectionists (NPs; 44%) and adaptive perfectionists (APs; 19%). Further analysis (MANCOVA) showed that while MPs have the highest tendencies toward workaholism and useless superiority effort, NONPs have the lowest tendencies toward these. Moreover, APs reported significantly lower useless superiority than NPs, despite scoring similarly on both narcissism and workaholism.  https://www.selleckchem.com/products/SRT1720.html  Additionally, based on workaholism being related to narcissism, high standards and discrepancy dimensions of perfectionism, as well as useless superiority effort, while weekly work hours are not, it can be suggested that workaholism is qualitatively different from working long hours.
  Evaluation and comparison 30-day readmission rate (
  ) from discharge within three year period and to note could it be a 
  in pediatric surgery.
 
  The case records of the patients that were readmitted within 30 days of primary surgery from January 1
  2017 to December 31
  2019 were identified retrospectively, for each year separately. Demographic data, diagnosis and the treatment on primary admission, length of hospital stay, and diagnosis with treatment on readmission, were collected. For each year readmissions were identified and divided into two groups (emergency and elective) based on the nature of the primary surgery. Outcomes were compared between two groups.
 
  A total of 5392 admissions were identified among three years (2017, 
   = 1821; 2018, 
   = 1806; 2019, 
   = 1765). There was 1014(55.6%) elective admissions in 2017, 953(52.8%) in 2018 and 950(53.8%) in 2019. The overall 
  rate was 0.82%, 0.99% and 0.57% for years 2017, 2018 and 2019, respectively (
   = 0.348). The most common cause for readmission was appendicitis related followed by surgical site infection in different subfields. The share of the number of readmissions during the three-year period is 3.2 times higher for emergency admissions than for elective admissions (
   < 0.001). The majority(>75%) of all readmission in all three years occurred in children above age of eight. Male gender was significantly more frequently associated with readmission(74.4%)(
   < 0.001).
 
  is a reproducible and good quality-of-care indicator in pediatric surgery. An incidence of 
  is significantly higher in emergency admissions and an appendectomy is the most common procedure associated with 
  .
 ReAd is a reproducible and good quality-of-care indicator in pediatric surgery. An incidence of ReAd is significantly higher in emergency admissions and an appendectomy is the most common procedure associated with ReAd.
  The aims of the presented case report are to emphasize the importance of a proper diagnostics and treatment in the case of the coexistence of Klinefelter syndrome (KS, 47 XXY) and complete androgen insensitivity syndrome (CAIS). Since there is no causal treatment it is necessary to provide the patient with a good quality of life, including psychological and sexological support.
 
  The presented case report is the retrospective analysis of the patient's medical history over the 3 years.
 
  At the age of 15, the patient was directed to genetic testing due to primary amenorrhea. The results of the patient showed an incorrect male karyotype with the SRY gene present (47, XXY). A molecular diagnostics revealed a very rare variant of the androgen receptor (AR) mutation responsible for tissue insensitivity to androgens. The detected mutation has not been described in the available databases so far. Following a diagnosis of the presence of Klinefelter syndrome (KS, 47 XXY) together with complete androgen insensitivity syndrome (CAIS), the patient underwent a bilateral gonadectomy.
 
  In women with KS and CAIS physiological reproduction and maintenance of normal sex, hormone levels are not possible. A gonadectomy is performed due to the risk of malignant testicular tumors.
 In women with KS and CAIS physiological reproduction and maintenance of normal sex, hormone levels are not possible. A gonadectomy is performed due to the risk of malignant testicular tumors.Introduction Paraneoplastic neurological syndromes (PNS) are a rare heterogeneous group of neurological diseases associated with tumors. These syndromes are the result of a cross-reactive immune response against antigens shared by the tumor and the nervous system. The discovery of an increasing number of autoantigens and the identification of tumoral factors leading to a substantial antitumoral immune response makes this topic highly innovative.Areas covered This review covers the clinical, oncological, pathophysiological aspects of both immunological PNS groups. One is associated with autoantibodies against intracellular onconeural antibodies, which are highly specific for an underlying tumor, although the disease is mainly T-cell mediated. In contrast, PNS associated with pathogenic surface-binding/receptor autoantibodies, which are often responsive to immunosuppressive treatment, may manifest as paraneoplastic and non-paraneoplastic diseases. The most frequent tumors associated with PNS are (small cell) lung cancer, gynecological tumors, thymoma, lymphoma, and, in children, neuroblastoma.