https://www.selleckchem.com/products/ml385.html When the coal gangue content exceeded 10%, the soil nutrient status was obviously improved. In the treatment group where the topsoil substitute material was fly ash, the chemical properties of reconstructed soil tended to deteriorate. In the treatment group where the topsoil substitute material was rock and soil stripping material, when the content of rock and soil stripping material exceeded 20%, the chemical properties of reconstructed soil were mostly better than those of the control scheme. The study of the different proportions of coal gangue, fly ash, and rock and soil stripping material as topsoil substitute materials provide support for reclamation work in mining areas where topsoil is scarce, as well as a reference for ecological restoration projects in grassland open-pit mining areas around the world.This study aimed to determine whether perceived environmental pollution is associated with subjective cognitive decline (SCD) or SCD-related functional difficulties. We conducted a cross-sectional study using data from a nationwide sample of 191,054 individuals aged ≥19 years from the 2018 Korea Community Health Survey. Perceived air, water, soil, noise, and green space pollution was assessed. To investigate the dose-response effect of the amount of perceived environmental pollution, we determined whether an increasing number of types of perceived environmental pollution also increased the odds of having SCD or SCD-related functional difficulties. Among the 191,054 individuals, the prevalence of SCD and SCD-related functional difficulties was 17.7% (N = 33,853) and 2.2% (N = 4139), respectively. Perception of air, soil, or noise pollution was significantly associated with SCD. However, the perception of any type of environmental pollution was not significantly associated with SCD-related functional difficulties. With regard to a dose-response effect, individuals perceiving a greater number of types of environment