005). Additionally, the standard deviation of the normal-to-normal interval, which decreases in the autonomic dysfunction state, was lower (P=0.030) during the hypoglycemic period. In panhypopituitarism, the low frequency to high frequency ratio during the hypoglycemic period was increased (P=0.007).
 
  HRV analysis during CPFT enables estimation of cardiac autonomic dysfunction in patients with NFPA who develop ACTH deficiency with other pituitary hormone deficiencies or panhypopituitarism after surgery. These patients may require a preemptive assessment of cardiovascular risk.
 HRV analysis during CPFT enables estimation of cardiac autonomic dysfunction in patients with NFPA who develop ACTH deficiency with other pituitary hormone deficiencies or panhypopituitarism after surgery. These patients may require a preemptive assessment of cardiovascular risk.
  We aimed to evaluate the clinicopathological features and biological behaviors of Korean thyroid cancer patients with rare variants of papillary thyroid carcinoma (PTC) to address the ambiguity regarding the prognostic consequences of these variants.
 
  We retrospectively reviewed the medical records of 5,496 patients who underwent thyroid surgery for PTC, between January and December 2012, in nine tertiary hospitals. Rare PTC variants included tall cell (TCV), columnar cell (CCV), diffuse sclerosing (DSV), cribriform-morular (CMV), solid (SV), hobnail, and Warthin-like variants. Recurrence-free survival (RFS) was defined as the time from the date of thyroidectomy until recurrence.
 
  Rare variants accounted for 1.1% (n=63) of the PTC patients; with 0.9% TCV, 0.02% CCV, 0.1% DSV, 0.1% CMV, and 0.1% SV. The mean age of patients and primary tumor size were 42.1±13.1 years and 1.3±0.9 cm, respectively. Extrathyroidal extension and cervical lymph node metastasis were observed in 38 (60.3%) and 37 (58.7%) patients, respectively. Ultrasonographic findings revealed typical malignant features in most cases. During a median follow-up of 7 years, 6.3% of patients experienced a locoregional recurrence. The 5-year RFS rates were 71.4% in patients with DSV or SV, 95.9% for TCV, or CCV, and 100% for other variants. DSV emerged an independent risk factor associated with shorter RFS.
 
  In this multicenter Korean cohort, rare variants accounted for 1.1% of all PTC cases, with TCV being the most frequent subtype. DSV emerged as a significant prognostic factor for RFS.
 In this multicenter Korean cohort, rare variants accounted for 1.1% of all PTC cases, with TCV being the most frequent subtype. DSV emerged as a significant prognostic factor for RFS.
  Older patients with mental disorders are particularly likely to be affected by negative consequences of the infection control measures that have been implemented as a result of the COVID-19pandemic.
 
  A questionnaire survey was sent to 18 departments of geriatric psychiatry from all four health regions in Norway.
 
  Altogether 83 therapists from various occupational groups responded, with representatives from all the health regions. Almost one-half (45.8%) reported an exacerbation of patients' mental condition to a large or very large degree due to social isolation, and an equal proportion (48.2%) reported that normal follow-up was limited. The contact between the specialist and primary health services was reduced, and 15.6% reported that patients had failed to receive the necessary somatic medical assistance to a large or very large degree.
 
  The service for older patients with mental disorders in the specialist health service was reduced as a result of the COVID-19pandemic, while coordination with the primary health service was also curtailed, and many patients deteriorated mentally as a result of the infection control measures. Collaboration between the specialist and primary health services may be an important focus area for this patient group.
 The service for older patients with mental disorders in the specialist health service was reduced as a result of the COVID-19 pandemic, while coordination with the primary health service was also curtailed, and many patients deteriorated mentally as a result of the infection control measures. Collaboration between the specialist and primary health services may be an important focus area for this patient group.
  Cataract surgery is a very common intervention. The objective of this study was to investigate the trends in the number of cataract surgeries in Norway and the characteristics of patients who underwent cataract surgery in the period 2010-19.
 
  Data on cataract surgery were collected from the Norwegian Patient Registry. The number of cataract surgeries per million inhabitants was calculated on the basis of population data from Statistics Norway.
 
  The number of cataract surgeries in Norway increased from 36340in 2010to 48291in 2019.This corresponded to an increase of 21%, from 7480to 9063per million inhabitants respectively, in the same period. The average age was 74years, and more than 90% of the patients were above the age of 60.The proportion of cataract surgeries among patients older than 60years remained virtually unchanged through the study period. Women accounted for 60% of the cataract surgeries in 2010and 57% in 2019.The proportion of surgeries performed by contract specialists in the entire period varied from 32% in Central Norway Regional Health Authority to 62% in Northern Norway Regional Health Authority.
 
  The number of cataract surgeries increased throughout the period in pace with the population growth in the age group above 60years. With further population growth and an increasing number of older people, planning for a further increase in the number of cataract surgeries in future years is likely to be required.
 The number of cataract surgeries increased throughout the period in pace with the population growth in the age group above 60 years. With further population growth and an increasing number of older people, planning for a further increase in the number of cataract surgeries in future years is likely to be required.
  The purpose of the study was to investigate health-related help-seeking behaviour among illegal substance users.
 
  Data were collected on the website Rusopplysningen.no. Questions were asked about use of illegal substances and openness with healthcare personnel regarding this use.  https://www.selleckchem.com/products/alkbh5-inhibitor-2.html  Only respondents who reported having used illegal substances were included, and missing responses to particular questions were excluded from the percentage calculations.
 
  Altogether 2485 respondents had used illegal substances. A total of 880 (39%) had told healthcare/social care personnel about their substance use, of which 506 (68%) reported that they had no need of help. Altogether 802 (36%) had avoided telling healthcare/social care personnel about their use of illegal substances in relevant situations, while 309 (14%) believed that they needed treatment for substance use, and 202 of these (65%) had avoided or postponed seeking such treatment. Among the 815 who had been in an acute medical situation related to substance use, 82 (10%) had delayed calling an ambulance, and 330 (41%) had avoided calling an ambulance altogether.