Micro/nanomotors (MNMs) are miniature machines that can convert chemical or external energy into their own mechanical motions. In previous decades, significant efforts have been made to improve the performance of MNMs. For practical applications, the biodegradability of MNMs is an important aspect that must be considered, particularly in the biomedical field. In this review, recent progress in the biodegradability of MNMs and their potential applications are summarized. Different biodegradable materials, including metals and polymers, or other strategies for the fabrication of MNMs, are presented. Current challenges and future perspectives are also discussed.Two Cp*-RhIII based trefoil knots were obtained in high yield under ambient conditions via the coordination-driven self-assembly of semi-rigid thioether dipyridyl ligand 1,4-bis[(pyridin-4-ylthio)methyl]benzene (L1 ), ligand chloranilic acid (H2 -CA) and 6,11-dihydroxytetracene-5,12-dione (H2 -TtDo) with Cp*RhIII metal corner units, respectively. Furthermore, using the bulkier 4,4'-[(2,5-dimethyl-1,4-phenylene)bis(methylene)]bis(sulfanediyl)dipyridine (L2 ) in the place of ligand L1 in the construction process resulted in the formation of a teranuclear metallacycle and a template-free Borromean ring in high yields thanks to significantly altered intermolecular forces between the constituent ligands induced by the sterically-hindering methyl groups of L2 , as demonstrated via a detailed X-ray crystallographic analysis and NMR spectroscopy.It is a great challenge to refine precious metals from e-wastes under mild conditions without hazardous reagents. Herein, black phosphorus (BP) was covalently functionalized with poly(N-isopropylacrylamide) (PNIPAM) to obtain thermo/near-infrared (NIR)-responsive BP-P for precious metal recovery. Precious metals (Au, Ag, and Pd) with higher redox potentials than BP-P could be efficiently recovered by reduction-driven enrichment. Taking Au as an example, the recovery process presented fast kinetics ( less then 15 min), excellent selectivity, and high efficiency (≈98 %). Remote operation with NIR light could generate heat by BP, which induced the hydrophilic-to-hydrophobic transition of PNIPAM, allowing the spontaneous gathering, facile collection, and practical recycle of BP-P following Au extraction. Thanks to the unique features of BP-P, not only could high-quality Au nanoparticles (20-30 nm) be economically extracted (cost $0.731-1.222 g-1 Au nanoparticles; 5-6 orders of magnitude lower than the market price), but also the formed BP-P-Au nanocomposites have potential application in hydrogen evolution reaction.
  Conditional survival (CS) and failure hazard estimations can provide important dynamic prognostic information for clinical decision-making and surveillance counseling. The current study aimed to investigate the CS and dynamic failure hazard in non-metastatic nasopharyngeal carcinoma (NPC) treated with intensity-modulated radiotherapy (IMRT).
 
  Conditional overall survival (COS) and progression-free survival (CPFS) estimates adjusted for age and gender against each AJCC 8th stage were calculated. Multivariable Cox regression (MCR) models were fitted in the entire population at baseline and subsequently separate MCR models were fitted in patients who have maintained event-free time of 1 to 10years to generate respective hazard ratio (HR). Annual hazard rates of death and progression over 10years for each stage were also estimated.
 
  A total of 1993 patients were eligible for analysis. The estimated 5-year OS and PFS for entire cohort were 79.0% and 70.7% at initial diagnosis. After 5years of event-free followc NPC improves over years with distinct dynamic patterns across stages, providing important implications for personalized decision-making in terms of both clinical management and surveillance counseling.  https://www.selleckchem.com/products/oxidopamine-hydrobromide.html  Stage-dependent and hazard-adapted clinical management and surveillance are warranted.
  To investigate the manifestation, mechanisms, and treatment of isolated partial femoral avulsion fractures of the posterior cruciate ligament (PCL) in adults.
 
  From January 2011 to December 2018, we retrospectively reviewed the clinical data of three patients with isolated partial femoral avulsion fractures of the PCL who were admitted to our institution. All of these patients were admitted to our emergency department within 24 h after injury. After physical examination and radiographs were taken and reviewed, all patients were admitted and underwent surgical treatment. In a 26-year-old man who underwent arthroscopic surgery through the traditional medial and lateral approach before finally converting to open surgery with the posterior approach, the fragment that was finally removed was partially attached to the PCL. In the other two patients, women aged 63 and 68 years, who underwent arthroscopic surgery via the traditional medial and lateral approach, the fragments were large and attached to most fibers ent of these patients. Most of these fractures can be repaired by arthroscopic surgery, but some have to be treated by open surgery.
 The manifestation of isolated partial femoral avulsion fractures of the PCL in adults is often related to the injury mechanism, and surgery is essential for the treatment of these patients. Most of these fractures can be repaired by arthroscopic surgery, but some have to be treated by open surgery.Cardiovascular diseases account for the highest mortality globally, but recent advances in wearable technologies may potentially change how these illnesses are diagnosed and managed. In particular, continuous monitoring of cardiovascular vital signs for early intervention is highly desired. To this end, flexible wearable sensors that can be comfortably worn over long durations are gaining significant attention. In this review, advanced flexible wearable sensors for monitoring cardiovascular vital signals are outlined and discussed. Specifically, the functional materials, configurations, mechanisms, and recent advances of these flexible sensors for heart rate, blood pressure, blood oxygen saturation, and blood glucose monitoring are highlighted. Different mechanisms in bioelectric, mechano-electric, optoelectric, and ultrasonic wearable sensors are presented to monitor cardiovascular vital signs from different body locations. Present challenges, possible strategies, and future directions of these wearable sensors are also discussed.