https://www.selleckchem.com/products/gc7-sulfate.html heir midwifery skills and work to their potential.Beyond the direct physiological functions associated with motherhood in mammals, previous studies have suggested the potential role of prolactin (Prl) in distinct brain processes such as neuroprotection, neurogenesis, and stress responses. However, the cognitive influence of Prl remains unclear, particularly regarding the mechanisms of acquisition, consolidation and retrieval of information in the brain. Using chronic implanted electrodes in freely moving female mice combined with behavioral tests, we investigated the rhythmic activity changes induced by Prl in a model of hippocampus-dependent learning and memory. Our results show that Prl improves the learning of a spatial memory task in the acquisition stage. The main variations at the circuitry level were in the theta frequency band (4-8 Hz and 8-12 Hz), marked by a faster change in oscillatory activity with no modifications to higher frequencies. These results show that Prl plays a significant role in the acquisition of information during learning of a spatial memory task, suggesting that an increase in Prl levels may induce changes in circuital network plasticity.Previous research indicates that circulating concentrations of cortisol increase during interactions with opposite-sex others in the presence of mating cues. However, it remains unknown whether this phenomenon extends to work-related tasks in which explicit mating cues are absent. In a series of two studies, we assessed women's and men's salivary cortisol concentrations before and after completing a cooperative brainstorming (Study 1) and competitive negotiation (Study 2) task wherein they worked with same- or opposite-sex partners. Both studies revealed significant participant sex by partner sex interactions. Specifically, male participants demonstrated significantly larger increases in salivary cortisol concentrations when working alongside opposit