Purpose To report a modified surgical technique for chandelier endoillumination-assisted scleral buckling using an endolaser. Methods A three patient case reports for demonstration of surgical technique. Results All patients underwent successful primary retinal detachment repair without any intraoperative or post-operative complications. Conclusion Endolaser can be employed during chandelier endoillumination assisted scleral buckling either as a standalone tool or in conjunction with cryopexy, especially in cases with posteriorly located retinal breaks. © 2020 Yannuzzi et al.Purpose In ophthalmology, injuries due to lightning strikes have been documented as various entities ranging from keratitis, cataracts, uveitis in the anterior segments to retinal detachments, papillitis, and macular hole formation in the posterior segment. We report the largest case series so far with a total of seven cases of lightning injuries with ocular involvement and its management and a brief review of the literature on this topic. Patients and Methods All of the patients were evaluated for ocular injuries due to a lightning strike and each of the cases has been individually described as case series with their findings and management in this report. Results Ocular injuries caused by lightning are very rare, but when they occur, they can present with various ocular tissue pathology-ranging from anterior to the posterior segment structures. Most of the cases presented with maculopathy and foveschitic lesions, which resolved over time with the use of steroids. Conclusion Lightning injuries to the eyes, if detected early and managed appropriately, have a very good prognosis. The recovery is usually good with minimal functional loss if there is a quick referral. The macular region seems to be particularly involved in most cases and OCT can be a valuable diagnostic tool to detect and monitor the pathology. © 2020 Pradhan et al.Purpose To evaluate the corneal pachymetric and topographic parameters of systemic Lupus Erythematosus (SLE) patients using Dual Scheimpflug Imaging. Methods This observational cross-sectional controlled study included the right eye of 30 SLE patients and 30 age-matched controls. Corneal measurements were acquired by dual Scheimpflug imaging including anterior and posterior corneal curvatures, central, mid-peripheral corneal thickness (measured at the 5 mm zone) and peripheral pachymetry (measured at the 7 mm zone). SLE disease activity index (SLEDAI) was calculated and correlated with corneal pachymetry. Results SLE patients had significantly thicker corneal periphery than controls. Mean central corneal pachymetry was 530.4± 27.3 microns (SD) in SLE and 547.5±31.5 microns (SD) in control group, p = 0.032. The corneal periphery - except superiorly - was significantly thicker in SLE patients than controls (p ˂0.001). Nasal peripheral corneal thickness positively correlated with disease activity index SLEDAI (p=0.03). Conclusion SLE patients present with thicker corneal periphery than controls characteristically sparing the superior quadrant. Possible corneal photosensitivity leading to peripheral immune complex deposition as well as flatter posterior corneal surface at the periphery are proposed explanations for these findings. © 2020 Eissa et al.Purpose To analyze the subclinical intraocular involvement using multimodal imaging approach in patients affected by Erdheim-Chester disease (ECD) without ocular symptoms. Patients and Methods In this prospective cross-sectional study, 18 eyes of 9 consecutive patients with ECD were enrolled. Each patient underwent comprehensive ocular examination and extensive multimodal chorioretinal imaging. Results None of the patients presented any evidence of chorioretinal localization of disease using multimodal imaging. One patient exhibited a choroidal nevus complicated by active polypoidal choroidal neovascularization. Subretinal hyperreflective material was seen in three eyes, mainly resembling acquired vitelliform lesion. One patient had an isolated intraretinal hemorrhage. Most patients exhibited peripheral vascular abnormalities (ie, microaneurysms, peripheral vascular leakage). Fundus autofluorescence showed faint hyperautofluorescence in eleven eyes. Conclusion Intraocular involvement is an extremely rare event of an extremely rare disease. In patients affected by ECD without ocular symptoms, advance multimodal imaging examinations did not show signs of subclinical chorioretinal involvement related to the disease. © 2020 Sacconi et al.Purpose To evaluate the gender-related differences in demographic and ocular biometric trends in a defined population presenting for consultation within the Italian public health system and to collect data of several ocular parameters at different stages of life, highlighting the differences between females and males. Patients and Methods In this retrospective study, keratometry, corneal astigmatism, and axial eye length of 729 patients (729 eyes; mean age 58±21 years; range 18-96 years) were evaluated using partial coherence interferometry.  https://www.selleckchem.com/products/dibutyryl-camp-bucladesine.html  Statistical evaluation was performed utilizing a paired t-test and R2 analysis. Results In females (396 eyes of 396 patients), mean keratometry ranged between 40.59-47.78 D (44.27±1.36 D), corneal astigmatism ranged between 0-3.82 D (1.13±0.74 D), and axial length ranged between 20.5-31.32 mm (24.07±1.74 mm). In males (333 eyes of 333 patients), mean keratometry ranged between 38.5-46.95 D (43.54±1.35 D; p less then 0.001), corneal astigmatism ranged between 0.1-3.97 D (1.15±0.79; p=0.75), and axial length ranged between 20.41-31.21 mm (24.57±1.78 mm; p less then 0.001). Both genders presented a shorter axial length in advanced age. Elderly males presented a higher percentage of against-the-rule astigmatism. Conclusion Females may have steeper corneas and shorter eyes. A trend toward axial length reduction with age was observed in both genders. This finding is probably due to the difference in growth between generations, as the new ones have an higher size than the old ones. © 2020 De Bernardo et al.[Purpose] The primary purpose of this study was to evaluate the usefulness of the intraclass correlation coefficient for evaluating the reliability of the measurement of the supraspinatus thickness on shoulder ultrasonography at different angles in a resting position in patients with stroke. [Participants and Methods] The study included 20 patients with stroke. The supraspinatus thickness was measured on both sides on ultrasonography, with the participants' shoulders in abduction at 3 testing angles (0°, 30°, and 60° abduction). Each measurement was performed three times, and the average of the three measurements was recorded. The intraclass correlation coefficient was calculated, with the supraspinatus thickness measured twice at an interval of 24 hours as the factor. [Results] All intraclass correlation coefficients for the hemiplegic and normal sides were greater than 0.93 when the shoulders were at the three testing angles. [Conclusion] In this investigation, the reliability of measuring the supraspinatus thickness on shoulder ultrasonography at each angle for 3 times was evaluated and was found to be excellent.