https://www.selleckchem.com/pharmacological_epigenetics.html This review is the sequel to the 2000 report on the recent advances in the chemistry of odorants and it summarizes the developments in fragrance chemistry over the past 20 years. Following the olfactory spectrum set out in that report, trendsetting so-called captive odorants (patent-protected ingredients unavailable to the market) are presented according to the main odor families "fruity", "marine", "green", "floral", "spicy", "woody", "amber", and "musky". The design of odorants, their chemical synthesis, and their use in modern perfumery are illustrated with prominent examples. Also featured are new fruity odorants that provide signature in the top notes, as well as precursor technology. In the green domain, focus is on leafy notes and green pear. New benzodioxepines and benzodioxoles have modernized the marine family and required a revision of the existing olfactophore models. The replacement of Lilial and Lyral kept the industry busy in the floral domain with a plethora of new 'muguets'. There was continued activity in the domain of rose odorants, especially in the area of rose ketones. Biotechnology became significant, for example, with Clearwood and Ambrofix, and the principal odorants of vetiver oil in the woody family have been found. Fourth and fifth families of musk odorants were also discovered and populated. Thus, new avenues for further explorations into fragrance chemistry have been opened.Metal-organic frameworks (MOFs) are a class of versatile materials for fabricating functional heterogeneous catalysts, but the most routine method is through carbonization to form porous carbon materials, which however inevitably losses their inherent MOFs characteristics. Herein, we developed a partially-controlled pyrolysis strategy to create evenly distributed NiO nanoparticles within NiFe-MOF nanosheets (MOF NSs) for electrochemical synthesis of hydrogen peroxide (H2O2) via two-electron oxygen reduction