https://www.selleckchem.com/products/penicillin-streptomycin.html The results of the KPI survey indicated significant progress in the status of implementing GRevPs over the last ten years. To accelerate regulatory convergence among APEC economies, it is necessary to promote mutual trust and cooperation in approval of medical products over the time. Continuous training in GRevPs and GSubPs through the CoE platform would set the stage to achieve the goal in the next decade. To accelerate regulatory convergence among APEC economies, it is necessary to promote mutual trust and cooperation in approval of medical products over the time. Continuous training in GRevPs and GSubPs through the CoE platform would set the stage to achieve the goal in the next decade.The objective of the study was to evaluate the circulating levels of chemical elements after exercise-induced muscle damage (EIMD) followed by the repeated bout effect (RBE). Seven physically active subjects (26.5 ± 4.0 years) performed two sessions of EIMD (5 sets of 20 drop jumps), the second session 14 days after the first for RBE assessment. Blood collections, countermovement jump (CMJ), squat jump (SJ), and delayed-onset muscle soreness (DOMS) were performed before (Pre), after (Post), and 24, 48, and 72 h after the exercise session. Creatine kinase (CK) was detected by biochemical analysis and the concentration of chemical elements by total reflection X-ray fluorescence (TXRF). Differences between time points and sessions were assessed with two-way ANOVA and the effect size (ES). EIMD induced a reduction in the CMJ at 24 h (P  0.05). EIMD induced a large to very large ES for Zn reduction at 24 h (- 1.37) and 72 h (- 0.93) and Br (- 0.83) at 72 h. RBE presented large to very large ES for the increase in P at 48 h (0.92); Cl at 24 h (1.04); K at 24 h (0.91), 48 h (1.10), and 72 h (0.96); Ca at 72 h (0.92); and Fe at 24 h (0.85). RBE influenced the concentration of elements associated with fatigue (K, Ca, Cl), inf