Ultrasound data (UBM and A-scan) of eyelid tumors was highly correlated to histological features. Conclusion UBM with A-scan can be recommended for differential diagnostics of small-sized tumors and optimizing their management.In order to achieve a persistent hypotensive effect in primary open-angle glaucoma, a modification of the sinustrabeculectomy operation - modified sinustrabeculectomy with basal iridectomy combined with deep sclerectomy involving drainage of the anterior chamber and suprachoroidal space have been developed at the Department of Eye Diseases of the People's Friendship University of Russia. Purpose Development of a new method of surgical treatment of primary open-angle glaucoma based on sinustrabeculectomy with basal iridectomy in combination with deep sclerectomy involving drainage of the anterior chamber and suprachoroidal space by autosclera, and evaluation of the surgical outcomes. Material and methods The study analyses the results of surgical treatment of 19 patients (19 eyes) with glaucoma, who underwent sinustrabeculectomy with basal iridectomy in combination with deep sclerectomy and drainage of the anterior chamber and suprachoroidal space. Results The level of intraocular pressure (IOP) on the first day after surgery decreased from 14 mm Hg to 17.5 mm Hg in the late postoperative period (after 12 months), IOP of 18 patients had normalized and stabilized (IOP averaged 17.0±1.8 mm Hg); in 1 case there was an increase in IOP level, for which hypotensive therapy was prescribed (β-blockers). Conclusion Modified sinustrabeculectomy with basal iridectomy in combination with deep sclerectomy and drainage of the anterior chamber and suprachoroidal space by autosclera helps achieve a persistent hypotensive effect and does not require the use of donor material.Purpose To evaluate light scattering ability of the cornea before and after Descemet's stripping automated endothelial keratoplasty (DSAEK) and Descemet's membrane endothelial keratoplasty (DMEK) endothelial keratoplasty. Material and methods The study included 70 patients (70 eyes) who had undergone DSAEK and DMEK (35 patients, 35 eyes in each group). In addition to standard ophthalmological examinations before and during the one-year follow-up after surgery, the patients had their central corneal thickness, stromal thickness, thickness of the interface area and the graft measured with optical coherence tomography (Optovue, U.S.A.). Intensity of light scattering by corneal structures was evaluated using Pentacam HR (Oculus, Germany) topographer with proprietary software and algorithms for calculation of corneal transparency. Results Comparison of the outcomes revealed that indices of general integral and stromal light-scattering were higher in patients after DSAEK. Integral light scattering in the interface and graft areas in the DMEK group was significantly lower than in the DSAEK group during the whole follow-up period. Conclusion The reason for decrease of visual acuity after endothelial keratoplasty, regardless of the surgery type, may be higher light-scattering ability of patient's corneal stroma due to residual opacifications. Better visual acuity outcomes after DMEK in comparison to DSAEK are associated with higher transparency of the interface and graft areas. The suggested new method of assessing the intensity of light-scattering allows more precise evaluation of the influence of light-scattering ability of the stroma, interface and corneal graft after different modifications of endothelial keratoplasty, considering the respective layer thickness and excluding the influence of light scattering on the air-epithelium interface.Tractional flap tears are the main cause of the development of regmatogenic retinal detachment (RRD). The main immediate treatment method for it is laser retinal coagulation. Purpose Case monitoring of tractional symptomatic flap tears after laser treatment. Material and methods From 2014 to 2019 we observed 119 patients (130 eyes) with peripheral flap (horseshoe) retinal tears in acute posterior vitreous detachment. Laser coagulation of the retina was performed using Navilas 577s (577 nm), OcuLight GL (532 nm). Laser retinotomy of horseshoe tear flap and dissection of overhanging vessels were performed using NdYAG-ultra Q Reflex laser (1064 nm) and controlled with RTVue XR Avanti. Results At the initial examination before the preventive laser coagulation, the following conditions were found regmatogenous retinal detachment (RRD) - 8 eyes (6.2%), partial hemophthalmus - 29 (22.3%), preretinal hemorrhage - 15 (11.5%), epiretinal membrane - 9 (6.9%), non-full-thickness macular retinal breaks - 6 (4.6%), peripheral changes retinal holes - 16 (12.3%), tears with operculum - 5 (3.8%), retinal degenerations - 40 eyes (30.8%). Observation for 5 years after laser retinopexy revealed new pathological changes flap tears - 13 (10.6%); holes - 9 (7.4%); tears with operculum - 5 (4.1%); vitreoretinal tuft - 6 (4.9%); RRD - 3 cases (2.5%). In 16 patients (16 eyes) with horseshoe tear and pronounced vitreoretinal traction, the flap retinotomy was performed, which eliminated the traction component and prevented the development of RRD. Conclusion Follow-up of tractional symptomatic flap tears for 5 years after preventive laser retinopexy revealed the appearance of retinal detachment in 2.5% of cases. Laser retinotomy of horseshoe tear after barrier retinopexy eliminated the traction component and helped prevent the development of RRD.Purpose To evaluate clinical results of posterior lamellar keratoplasty performed with Russian femtosecond laser «Vizum» for treating patients with primary and secondary corneal endothelial dystrophies. Material and methods The study included 30 operated eyes 10 with Fuch's primary endothelial dystrophy of the cornea and 20 with secondary endothelial dystrophy. Patients were examined on the 7th day, as well as at 3, 6, 12 and 24 months after the surgery. All 28 patients (30 eyes) were followed-up for 12 months, 12 patients (14 eyes) were followed-up for 24 months. Results In 3 months after the surgery, transparent engraftment was observed in most cases. In 1 case, its primary failure was diagnosed and repeated keratoplasty was performed. Postoperative haze in host-donor interface was observed in 1 case.  https://www.selleckchem.com/products/abt-199.html  Central corneal thickness (CCT) was 554±43 µm. Transplant thickness in the central zone was 80±13 µm. The amount of eyes with Best Spectacle-Corrected Visual Acuity (BSCVA) of 0.3 was 43%. Endothelial cells density (ECD) was 1538±500 cells/mm2.