https://www.selleckchem.com/products/GDC-0941.html OBJECTIVES The ICEpop CAPability measure for adults (ICECAP-A) is a measure of capability well-being for adults and, by focusing on more than health, can extend the evaluative space of economic evaluations. The aim of this study was to translate and culturally adapt the ICECAP-A questionnaire into Persian to assess the construct validity and reliability of the ICECAP-A in the Iranian general population. METHODS In this study, we followed Beaton's guidelines for cross-cultural adaptation of self-report measures. The questionnaire was administered to a sample of 1200 members of the general population using a stratified probability sampling method. The construct validity and reliability of the ICECAP-A were evaluated in relation to the EuroQol 5-dimension questionnaire (EQ-5D-5L). RESULTS After translating and adapting the questionnaire, the term "being settled" was changed to "stability" for the Iranian cultural context. A moderate correlation (r = 0.48) was found between the ICECAP-A and EQ-5D-5L index scores, and the ICECAP-A scores showed differences across different health and socio-economic groups. The results of the exploratory factor analysis indicated that the 2 instruments measured 2 different constructs. In terms of reliability, the internal consistency of the measure using Cronbach's alpha was found to be 0.82 and for test-retest reliability, the intraclass correlation coefficient (ICC) was found to be 0.90 for total scores. CONCLUSIONS The results of this study suggest that the Persian version of the ICECAP-A is a valid and reliable questionnaire and can complement EQ-5D measures already used in Iran. Alternating trilinear decomposition (ATLD) method enables the qualitative and quantitative analysis of excitation-emission matrix fluorescence (EEMF) data acquired from complex samples. However, the impact of diverse background interferences from different sample sources on the performances of ATLD method has