Dynorphin activation of KOR promoted microglial M2 polarization via inhibiting TLR4/NF-κB pathway in LPS-stimulated BV-2 microglial cells. Moreover, dynorphin/KOR regulated microglial M2 polarization inhibited apoptosis of the primary mouse hippocampal neurons. Conclusion In conclusion, dynorphin activation of KOR promotes microglia polarization toward M2 phenotype via inhibiting TLR4/NF-κB pathway. © The Author(s) 2020.[This corrects the article DOI 10.1093/jscr/rjz327.]. Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is a rising cause of skin and soft tissue infections over the last decade with potentially serious complications.  https://www.selleckchem.com/products/bay80-6946.html  In this article, we describe a case of a large scalp and post-auricular abscess complicated by bacteremia. This is a case of a 73-year-old female who presented with altered mental status was found to have two fluctuant scalp abscesses, bacteremia with necrosis. The patient was promptly treated with intravenous antibiotics, multiple operative debridements without calvarial periosteum involvement defects requiring split-thickness skin grafts for wound closure. This case highlights the severity of a CA-MRSA skin infection in an atypical location. Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.The common house spider Parasteatoda tepidariorum, belonging to the Chelicerata in the phylum Arthropoda, has emerged as an experimental system for studying mechanisms of development from an evolutionary standpoint. In this article, we review the distinct characteristics of P. tepidariorum, the major research questions relevant to this organism, and the available key methods and resources. P. tepidariorum has a relatively short lifecycle and, once mated, periodically lays eggs. The morphogenetic field of the P. tepidariorum embryo is cellular from an early stage and exhibits stepwise symmetry-breaking events and stripe-forming processes that are associated with body axes formation and segmentation, respectively, before reaching the arthropod phylotypic stage. Self-regulatory capabilities of the embryonic field are a prominent feature in P. tepidariorum. The mechanisms and logic underlying the evolvability of heritable patterning systems at the phylum level could be one of the major avenues of research investigated using this animal. The sequenced genome reveals whole genome duplication (WGD) within chelicerates, which offers an invertebrate platform for investigating the potential roles of WGD in animal diversification and evolution. The development and evolution of lineage-specific organs, including the book lungs and the union of spinnerets and silk glands, are attractive subjects of study. Studies using P. tepidariorum can benefit from the use of parental RNA interference, microinjection applications (including cell labeling and embryonic RNA interference), multicolor fluorescence in situ hybridization, and laser ablation as well as rich genomic and transcriptomic resources. These techniques enable functional gene discoveries and the uncovering of cellular and molecular insights. © The Author(s) 2020.The aesthetic experience of the perceiver of art has been suggested to relate to the art-making process of the artist. The artist's gestures during the creation process have been stated to influence the perceiver's art-viewing experience. However, limited studies explore the art-viewing experience in relation to the creative process of the artist. We introduced eye-tracking measures to further establish how congruent actions with the artist influence perceiver's gaze behaviour. Experiments 1 and 2 showed that simultaneous congruent and incongruent actions do not influence gaze behaviour. However, brushstroke paintings were found to be more pleasing than pointillism paintings. In Experiment 3, participants were trained to associate painting actions with hand primes to enhance visuomotor and visuovisual associations with the artist's actions. A greater amount of time was spent fixating brushstroke paintings when presented with a congruent prime compared with an incongruent prime, and fewer fixations were made to these styles of paintings when presented with an incongruent prime. The results suggest that explicit links that allow perceivers to resonate with the artist's actions lead to greater exploration of preferred artwork styles. © The Author(s) 2020.Improvement of water splitting performance of AgTaO3 (BG 3.4 eV) of a valence-band-controlled photocatalyst was examined. Survey of cocatalysts revealed that a Rh0.5Cr1.5O3 cocatalyst was much more effective than Cr2O3, RuO2, NiO and Pt for water splitting into H2 and O2 in a stoichiometric amount. The optimum loading amount of the Rh0.5Cr1.5O3 cocatalyst was 0.2 wt%. The apparent quantum yield (AQY) at 340 nm of the optimized Rh0.5Cr1.5O3(0.2 wt%)/AgTaO3 photocatalyst reached to about 40%. Rh0.5Cr1.5O3(0.2 wt%)/AgTaO3 gave a solar to hydrogen conversion efficiency (STH) of 0.13% for photocatalytic water splitting under simulated sunlight irradiation. Bubbles of gasses evolved by the solar water splitting were visually observed under atmospheric pressure at room temperature. This journal is © The Royal Society of Chemistry 2020.Successful exploitation of semiconductor nanocrystals (NCs) in commercial products is due to the remarkable progress in the wet-chemical synthesis and controlled assembly of NCs. Central to the cadence of this progress is the ability to understand how NC growth and assembly can be controlled kinetically and thermodynamically. The arrested precipitation strategy offers a wide opportunity for materials selection, size uniformity, and morphology control. In this colloidal approach, capping ligands play an instrumental role in determining growth parameters and inter-NC interactions. The impetus for exquisite control over the size and shape of NCs and orientation of NCs in an ensemble has called for the use of two or more types of ligands in the system. In multiple ligand approaches, ligands with different functionalities confer extended tunability, hinting at the possibility of atomic-precision growth and long-range ordering of desired superlattices. Here, we highlight the progress in understanding the roles of ligands in size and shape control and assembly of NCs.