Students' bonding to school varied based on gender and grade, with females and younger students being generally more bonded to school. There were strong correlations between valuing fitness and having an interest in athletic activities (r = .599) and valuing education and having an interest in the arts (r = .340). Bonding to school was strongly correlated with only two values education (r = .435) and character (r = .335). Having an interest in technology was not correlated with any of the 15 values or students' bonding to school. Results suggest that interventions and policies that wish to improve bonding to school might do well to take advantage of existing highly ranked positive values and provide an opportunity for students to engage in a wide array of activities of interest.Pest and plant diseases cause damages and economic losses, threatening food security and ecosystem services. Thus, proper pest management is indispensable to mitigate the risk of losses. The risk of environmental hazards induced by toxic chemicals alongside the rapid development of chemical resistance by insects entails more resilient, sustainable, and ecologically sound approaches to chemical methods of control. This study evaluates the application of three dynamical measures of controls, namely, green insecticide, mating disruption, and the removal of infected plants, in controlling pest insects. A model was built to describe the interaction between plants and insects as well as the circulation of the pathogen. Optimal control measures are sought in such a way they maximize the healthy plant density jointly with the pests' density under the lowest possible control efforts. Our simulation study shows that all strategies succeed in controlling the insects. However, a cost-effectiveness analysis suggests that a strategy with two measures of green insecticide and plant removal is the most cost-effective, followed by one which applies all control measures. The best strategy projects the decrease of potential loss from 65.36% to 6.12%.Due to the emergence of a new SARS-CoV-2 variant, we use a previous model to simulate the behaviour of this new SARS-CoV-2 variant. The analysis and simulations are performed for Europe, in order to provide a global analysis of the pandemic. In this context, numerical results are obtained in the first 100 days of the pandemic assuming an infectivity of 70%, 56%, and 35%, respectively, higher for the new SAR-CoV-2 variant, as compared with the real data.Fully metallic micrometer-scale 3D architectures can be fabricated via a hybrid additive methodology combining multi-photon lithography with electrochemical deposition of metals.  https://www.selleckchem.com/products/cmc-na.html  The methodology - referred to as two-photon templated electrodeposition (2PTE) - has significant design freedom that enables the creation of complicated, traditionally difficult-to-make, high aspect ratio metallic structures such as microneedles. These complicated geometries, combined with their fully metallic nature, can enable precision surgical applications such as inner ear drug delivery or fluid sampling. However, the process involves electrochemical deposition of metals into complicated 3D lithography patterns thicker than 500 μm. This causes potential and chemical gradients to develop within the 3D template, creating limitations to what can be designed. These limitations can be explored, understood, and overcome via numerical modeling. Herein we introduce a numerical model as a design tool that can predict growth for manufacturing complicated 3D metallic geometries. The model is successful in predicting the geometric result of 2PTE, and enables extraction of insights about geometric constraints through exploration of its mechanics.
  Behcet's Disease (BD) is an inflammatory disease characterized by multisystemic involvement and featured by a chronic, relapsing disease course. Recurrent ocular inflammation and macular involvement may lead to severe loss of visual acuity. Prolonged use of local and systemic corticosteroids lead to numerous side effects and complications. Very often other immunosuppressive therapies are needed. Biologic agents are promising for the treatment of Behcet's disease-associated uveitis.
 
  To report successful treatment of paediatric uveitis due to incomplete Behçet's disease with administration of adalimumab, after failing to react to all other modalities of treatment.
 
  We present the case of a 15-year-old girl who was treated for reccurent uveitis in both eyes with developed complications on anterior and posterior ocular segment. She was earlier treated with topical and systemic steroids for uveitis, laser photocoagulation and methotrexate, however, relapses occurred inspite all treatment modalities. Patient was diagnosed with incomplete Behcet's disease, and adalimumab therapy was initiated. Inflammation was well-controlled by adalimumab administration without need for local or systemic corticosteroids.
 
  Adalimumab is effective for treating children with Behcet's disease-associated uveitis. Control of ocular inflammation in our case was achieved without need for continuing local or systemic corticosteroids, thus preventing further complications and possible significant vision loss.
 Adalimumab is effective for treating children with Behcet's disease-associated uveitis. Control of ocular inflammation in our case was achieved without need for continuing local or systemic corticosteroids, thus preventing further complications and possible significant vision loss.
  Ulcerative colitis (UC) is a chronic inflammatory disease that affects colon while the incidence is increasing worldwide. The pathogenesis of the disease is complex and involves multi factors such genetic predisposition, defects in epithelial barrier and immune response as well as environmental factors. Combination UC with Hemophilia A, a hereditary hemorrhagic disorder, is very rare but can lead massive rectal bleeding that will be fatal for the patients.
 
  The case report present a case of a man with hemophilia A with rectal bleeding and recently diagnosed with ulcerative colitis.
 
  A 52 years old man presented with massive rectal bleeding since 3 days before admitted to hospital. The patient reported recurrent rectal bleeding for years but never continue for more than a week. He was previously diagnosed with hemophilia A since 34 years ago with factor VIII between 5 to 8 percent and receive recombinant human factor VIII routinely. Colonoscopy examination showed redness and ulcer along colon descendent and was confirmed for ulcerative colitis with histopathology analysis.