Exploring electrolytes of high safety is essential to pave the practical route for sodium-ion batteries (SIBs) toward their important applications in large-scale energy storage and power supplies. In this regard, ionogel electrolytes (IEs) have been highlighted owing to their high ionic conductivity, prominent electrochemical and thermal stability, and, more crucially, high interfacial wettability. However, present studies lack an understanding of the interaction of IEs, which determines the ion desolvation and migration. In this article, IEs comprising an SBA-15 host, an ionic liquid, sodium salt, and poly(vinylidene fluoride)-hexafluoro propylene (PVDF-HFP) have been proposed by mechanical ball milling and roller pressing. The component ratio has been optimized based on the balance between ionic conductivity and self-supporting capability of IEs. The optimal IEs showed sufficiently high ionic conductivity (2.48 × 10-3 S cm-1 at 30 °C), wide electrochemical window (up to 4.8 V vs Na+/Na), and high Na+ transference number (0.37). Due to the presence of SBA-15 and an ionic liquid, the IEs exhibited much improved thermal resistance than that of the conventional organic liquid electrolytes (OLEs). Furthermore, Fourier transform infrared (FT-IR) spectroscopy revealed the hydrogen bonding interaction between silanols and the dissolved salts, not only anchoring anions for immobilization but also promoting the dissociation of sodium salts. After being matched with the Na3V2(PO4)3 (NVP) cathode and metallic Na anode, the SIBs presented a specific discharge capacity of up to 110.7 mA h g-1 initially at room temperature with 92% capacity retention after 300 cycles. The improved safety and electrochemical performance provided insights into rationally regulating IEs and their interactions with the prospect of strengthening their practical applications in SIBs.Wearable energy storage and flexible body biomolecule detection are two key factors for real-time monitoring of human health in a practical environment. It would be rather exciting if one wearable system could be used for carrying out both energy storage and biomolecule detection. Herein, carbon fiber-based NiCoO2 nanosheets coated with nitrogen-doped carbon (CF@NiCoO2@N-C) have been prepared via a simple electrochemical deposition method. Interestingly, being a dual-functional active material, CF@NiCoO2@N-C exhibits excellent behaviors as a supercapacitor and prominent electrocatalytic properties, which can be applied for enzyme-free biosensor. It exhibits outstanding energy storage, high capacitive stability (94% capacitive retention after 10,000 cycles), and pre-eminent flexible ability (95% capacitive retention after 10,000 bending cycles), as well as high sensitivity for enzyme-free glucose detection (592  μA mM-1). Moreover, the CF@NiCoO2@N-C-based wearable supercapacitors would be used as self-powered energy systems for enzyme-free biosensors. Integrating with bluetooth, we have successfully developed a wearable self-powered enzyme-free smartsensor, remotely controlled using a smartphone for health monitoring in a practical environment. From this prospective study, it was found that the design of wearable self-powered smartsensors, demonstrating energy storage and enzyme-free biosensing in one system, provides a promising device for detecting body biomolecules, which has the potential to be implemented in the artificial intelligent fields.Contact guidance has been extensively explored using patterned adhesion functionalities that predominantly mimic cell-matrix interactions. Whether contact guidance can also be driven by other types of interactions, such as cell-cell adhesion, still remains a question. Herein, this query is addressed by engineering a set of microstrip patterns of (i) cell-cell adhesion ligands and (ii) segregated cell-cell and cell-matrix ligands as a simple yet versatile set of platforms for the guidance of spreading, adhesion, and differentiation of mesenchymal stem cells. It was unprecedently found that micropatterns of cell-cell adhesion ligands can induce contact guidance. Surprisingly, it was found that patterns of alternating cell-matrix and cell-cell strips also induce contact guidance despite providing a spatial continuum for cell adhesion. This guidance is believed to be due to the difference between the potencies of the two adhesions. Furthermore, patterns that combine the two segregated adhesion functionalities were shown to induce more human mesenchymal stem cell osteogenic differentiation than monofunctional patterns. This work provides new insight into the functional crosstalk between cell-cell and cell-matrix adhesions and, overall, further highlights the ubiquitous impact of the biochemical anisotropy of the extracellular environment on cell function.in English, Hungarian A solaris retinopathia a fotoreceptorok és a retina pigmentepitheliumának ultraibolya (UV) fény okozta fotokémiai és termikus károsodása. A behatás következtében a leggyakoribb panaszok között a visuscsökkenés, a homályos látás és a pozitív scotomák szerepelnek. A diagnózis alkotásában az optikai koherencia tomográfia (OCT), a mikroperimetria és a fluoreszcein angiográfia (FLAG) nyújt segítséget. A szerzők egy 18 éves férfi esetét mutatják be, aki prolongált napfény-expozíció után jelentkezett a Semmelweis Egyetem Szemészeti Klinikáján, mindkét szemet érintő centralis scotoma miatt. Az OCT-felvételeken a retina egyes rétegeiben folytonossághiányt és reflexiófokozódást figyeltünk meg, míg mikroperimetriás vizsgálattal a laesióknak megfelelően érzékenységcsökkenés volt tapasztalható. A féléves követés során a jobb retina folytonossághiánya csökkent, míg a bal oldal teljes restitúciót mutatott. A mikroperimetriás lelet az OCT-n látottakkal korrelált. A beteg szubjektív panasza a jobb szemén minimálisra csökkent, mindennapi életét nem korlátozza, a bal szemére megszűnt. A solaris retinopathiának jelenleg specifikus terápiája nincs. A panaszok és az eltérések kedvező esetben 3–6 hónap alatt normalizálódnak, ez felhívja a figyelmet a megfelelő tájékoztatás és a prevenció szerepére. Orv Hetil. https://www.selleckchem.com/products/2-nbdg.html 2020; 161(16) 632–636.