https://www.selleckchem.com/products/protokylol-hydrochloride.html With the strengths of zero carbon emission and high gravimetric energy density, hydrogen energy is recognized as a primary choice for future energy supply. Electrochemical water splitting provides a promising strategy for effective and sustainable hydrogen production through renewable electricity, and one of the immediate challenges toward its large-scale application is the availability of low-cost and efficient electrocatalysts for the hydrogen evolution reaction (HER). Given the enormous efforts in the exploration of potential transition-metal carbide (TMC) electrocatalysts, this review aims to summarize the recent advances in synthetic methods and optimization strategies of TMC electrocatalysts. Additionally, the perspectives for the development of novel efficient TMC-based catalysts are also proposed.Our main objective was to investigate the numbers of days necessary for the disappearance of the cough caused by an angiotensin-converting enzyme inhibitor (ACEI) subsequent to the discontinuation of treatment, and to identify the associated factors that contribute to the appearance of said cough and angioneurotic edema. We studied 1101 patients with hypertension treated with an ACEI for 15 years. A multivariate analysis of binary logistic regression was performed to identify predisposing cough factors. In the 1101 patients treated with ACEI, 270 were diagnosed as having a cough caused by an ACEI (24.5%). The average numbers of days until the cough disappeared was 6.06 ± 1.58 days. The significant predisposing factors of the cough were female sex (odds ratio [OR], 1.77; 95% confidence interval [CI], 1.31-2.39), previous diagnosis of obstructive sleep apnea (OR, 1.85; 95% CI, 1.31-2.61), and concomitant use of thiazides (OR, 1.50; 95% CI, 1.11-2.04). Statins were shown as a protective factor (OR, 0.69; 95% CI, 0.51-0.93). In the case of angioneurotic edema, 25 patients (2.3%) were diagnosed, without s