In particular, Cd accumulates strongly in sediments of Ming River and Aixinzhuang dam from Xingtai City. In upstream and downstream of FRS, the potential ecological risk is low, except in Yongnian County where high ecological risk was caused by Cd and Hg. These findings provide new insights into the pollution characteristics and assessment of the potential ecological risks induced by heavy metals along FRS, which suggest new directions should strategically tend to typical pollutants control by policy formulation and taking effective measures to prevent and manage heavy metal pollution in North China.Patients with postoperative Crohn's disease are difficult to manage because of their risk of experiencing a more severe course, multiple symptom confounders, and poor sensitivity of symptomatic remission to rule out intestinal inflammation. In this group, data are lacking on biologic therapeutic efficacy, and recommendations are lacking for those with multiple medication failures. Novel noninvasive testing can simultaneously exclude alternate causes of symptoms (serum C4, fecal fat, small intestinal bowel overgrowth breath testing) and assess intestinal inflammation (fecal calprotectin, endoscopic healing index). In addition, endoscopy-based disease activity assessment and management are required. Endoscopy should be performed within 6 months of surgery, and aggressive disease activity monitoring can be considered with colonoscopy every 1-2 years subsequently to ensure late recurrence is detected. Patients with multiple resections should be screened for short bowel syndrome. Predictive biomarkers are needed to guide medication selection in this high-risk population. Postoperative prophylactic biologic therapy is prudent for patients with preoperative biologic failure. However, there are no high-quality data to guide which agent should be selected. Selecting biologics with an alternative mechanism of action in those who had failed a biologic with adequate drug concentrations and selection of different agents in those with previous intolerance are reasonable. Significantly more study is required to assess the efficacy of therapies in this setting.Along with the rise of biological active granular activated carbon (bGAC) filtration as advanced treatment technology for wastewater treatment plant (WWTP) effluents, the mathematical representation of such systems is gaining increasing importance. This work introduces a model that describes the performance of bGAC-filters for Dissolved Organic Carbon (DOC) removal from a WWTP effluent. The DOC removal within bGAC-filters is accomplished by two mechanisms adsorptive removal and biological transformation. An appropriate representation of the adsorptive removal requires the DOC to be divided into fictive fractions according to its adsorbability. Likewise, a further DOC classification according to its biodegradability is necessary. Modeling a bGAC-filter then becomes a multi-component adsorption problem, with the simultaneous occurrence of DOC degradation within a biofilm. For dealing with this modeling task, this work integrated the Ideal Adsorbed Solution (IAS) theory into a traditional biofilm model compatible with the Activated Sludge Model (ASM) Framework. For the description of the adsorption dynamics, a Freundlich isotherm for the equilibrium and a pseudo first order model for the kinetics were selected. The biofilm consisted of heterotrophic bacteria able to oxidize DOC using oxygen as electron acceptor. The correctness of the model was evaluated using experimental data from a pilot plant. The predicted DOC breakthrough curve satisfactorily fitted the experimental measurements for empty bed contact times (EBCT) of 6, 12, 24 and 33 min. Moreover, the model predicted the relationship between EBCT, DOC removal and bGAC-filter lifespan. The developed model is the first that combines multi-component adsorption and biofilm kinetics in a wastewater treatment context.Being an energetic fuel, methane is able to support microbial growth and drive the reduction of various electron acceptors. These acceptors include a broad range of oxidized contaminants (e.g., nitrate, nitrite, perchlorate, bromate, selenate, chromate, antimonate and vanadate) that are ubiquitously detected in water environments and pose threats to human and ecological health. Using methane as electron donor to biologically reduce these contaminants into nontoxic forms is a promising solution to remediate polluted water, considering that methane is a widely available and inexpensive electron donor. The understanding of methane-based biological reduction processes and the responsible microorganisms has grown in the past decade.  https://www.selleckchem.com/products/Zileuton.html  This review summarizes the fundamentals of metabolic pathways and microorganisms mediating microbial methane oxidation. Experimental demonstrations of methane as an electron donor to remove oxidized contaminants are summarized, compared, and evaluated. Finally, the review identifies opportunities and unsolved questions that deserve future explorations for broadening understanding of methane oxidation and promoting its practical applications.Stormwater runoff pollution has become a key environmental issue in urban areas. Reliable estimation of stormwater pollutant discharge is important for implementing robust water quality management strategies. Even though significant attempts have been undertaken to develop water quality models, deterministic approaches have proven inappropriate as they do not address the variability in stormwater quality. Due to the random nature of rainfall characteristics and the differences in catchment characteristics, it is difficult to generate the runoff pollutographs to a desired level of certainty. Bayesian hierarchical modelling is an effective tool for developing complex models with a large number of sources of variability. A Bayesian model does not look for a single value of the model parameters, but rather determines a distribution of the model parameters from which all inference is drawn. This study introduces a Bayesian hierarchical linear regression model to describe a catchment specific runoff pollutograph incorporating the associated uncertainties in the model parameters.