https://www.selleckchem.com/products/fht-1015.html Humeral shaft fractures are relatively common, representing up to 5% of all fractures. Conservative management is the treatment of choice for most humeral shaft fractures and offers good functional and union outcomes. Age and oblique fractures of the proximal third are two risk factors for non-union. Surgical indication threshold should be lower for patients with these factors. Functional outcomes and union rates after plating and intramedullary nailing are comparable, but the likelihood of shoulder complications is higher with intramedullary nailing. Finally, there is no advantage to early exploration of the radial nerve even in case of secondary radial nerve palsy.Proximal humerus fracture (PHF) is the 3rd most common fracture over age 65, and its incidence increases with age. The combination of an aging population and a high incidence in geriatric patients constitute a serious potential public health concern. The treatment of PHF is debated. Recent publications report similar results of conservative versus surgical treatment in several types of fractures. Therapeutic decision based on a multiparametric analysis is recommended, there is yet no consensus on the parameters to be analyzed. A recent study suggests taking into consideration individual parameters in deciding the therapeutic strategy and provides a pragmatic treatment algorithm. We propose here a simplified version of this algorithm, guiding therapeutic decision between conservative treatment, osteosynthesis and arthroplasty. To study the effects of human herpes virus 6 (HHV-6) on the hippocampal volume in patients with mesial temporal sclerosis (MTS). HHV-6 may play an etiologic role in MTS. Previous studies found a possible association with febrile status epilepticus. Several investigators have reported a higher prevalence of HHV-6 in MTS resections compared to other epilepsy etiologies. We used FreeSurfer to segment cortical structures and obtain whol