Effective response to COVID-19 is related to sowing the seeds for humanistic self and empathic civilization, rather than blaming, scapegoating and xenophobia.The auditory N1 component has been gaining interest as a possible biomarker in schizophrenia (SCZ). N1 to right (RE) and left ear (LE) amplitudes and latencies were assessed using a monoaural auditory oddball paradigm in 12 SCZ subjects and 15 matched healthy controls (M=40.1±8.53 and 39.4±7.73, respectively). T-student test revealed no differences between RE and LE stimulation for N1 amplitude and latency to both groups. However, there were differences in peak-to-peak N1 amplitudes between the two groups for both LE (t=-3.067; ρ=0.003) and RE (t=-2.794; ρ=0.007). These findings strengthen auditory N1 has an electrophysiological biomarker for schizophrenia. The aim of this study was to evaluate the association of bruxism and treatment regimens among remitted bipolar patients. The total case group included 222 adult patients with BD. Diagnosis of bruxism was based upon the on 'self-reports' plus the outcome from the clinical examinations. The sample consisted of 112 (50.5%) bipolar patients with bruxism and 110 (49.5%) without bruxism. Remitted bipolar patients who were on mood stabilizer plus atypical antipsychotic treatment had lower bruxism rates than patients on other than bipolar patients on mood stabilizer treatment regimen (p=0.04) and bipolar patients on polypharmacy (p=0.01). Our findings have supported the existence of psychotropic drug-bruxism relation and atypical antipsychotic related therapeutic effect among bipolar patients. Our findings have supported the existence of psychotropic drug-bruxism relation and atypical antipsychotic related therapeutic effect among bipolar patients. Elderly patients with coronary heart disease often suffer adverse psychological reactions, such as anxiety and depression. The dual-track interactive nursing model is a nursing intervention aimed to provide specific and community nursing. For patients with chronic diseases, this model can improve the patients' self-management and rehabilitation. The effect of this model on the mental health of patients with chronic diseases has been unanimously recognized by researchers. In this study, a dual-track interactive nursing model intervention was conducted on the anxiety and depression in elderly patients with coronary heart disease to verify the psychological effect of the model. From June 2018 to June 2019, 136 elderly patients with coronary heart disease (mean age of 63.5±8.26 years) from three communities in Changsha, Hunan Province, China were selected as subjects. A total of 53 and 50 patients were identified in the intervention and the control groups, respectively. The control group underwent routine lonursing model intervention in the management of patients with coronary heart disease can improve the self-management and the mental health of patients with coronary heart disease. Breast cancer is the most common cancer in female population worldwide. In the psychological response to the disease some patients may develop Posttraumatic Stress Disorder (PTSD) symptomatology. The aim of this study was to examine the prevalence and structure of PTSD symptoms in Croatian patients following breast cancer and to identify some medical and psychological predictors of severity of these symptoms. 97 women, who were one month up to six years post-completion of all primary cancer therapy, participated in the study. The present research is cross-sectional with a mixed method approach. For the screening of PTSD symptoms PTSD Checklist - Civilian Version (Weathers et al. 1991) was used, with two open-ended questions added. Using the cutoff method, 21.6% participants met criteria for PTSD diagnosis. Qualitative analysis indicated future-oriented intrusive thoughts about reoccurrence of cancer, multidimensional nature of cancer as stressors, and hyperarousal symptoms related to internal stimuli. https://www.selleckchem.com/products/lee011.html Ild be considered as significant, taking into account the lifetime prevalence of PTSD in the general female population. Psychological assessment of women following breast cancer should more often include an assessment of posttraumatic stress reactions. Furthermore, results are in the line with issues of utilizing basic concept of PTSD in the oncology setting, and possible need of reconceptualization of cancer-related PTSD. Although an inverse relationship between body mass index (BMI) and Parkinson disease (PD) has been repeatedly reported, to our knowledge, the relationship between BMI and antipsychotic-induced extrapyramidal symptoms (EPS) has rarely been studied in patients with schizophrenia. Our study aimed to evaluate the relationship between BMI and EPS in patients with schizophrenia. Using data from the Research on Asian Psychotropic Prescription Patterns for Antipsychotics (REAP-AP) study, we compared the prevalence of EPS in 1448 schizophrenia patients stratified as underweight, normal range, overweight pre-obese, overweight obese I, overweight obese II, and overweight obese III according to the World Health Organization (WHO) classification system for body weight status, and with underweight, normal range, overweight at risk, overweight obese I, and overweight obese II according to the Asia-Pacific obesity classification. In the first step of the WHO classification system for body weight status, adjusting for t that underweight was associated with a greater rate of muscle rigidity in a stepwise pattern among Asian patients with schizophrenia. Although the mechanism underlying the inverse relationship between BMI and muscle rigidity cannot be sufficiently explained, it is speculated that low BMI may contribute to the development of muscle rigidity regardless of antipsychotic "typicality" and dose in patients with schizophrenia. Attention deficit hyperactivity disorder (ADHD) is the most common psychiatric disorder in children. Several hypotheses have been proposed to explain its etiology. Mitochondrial dysfunction (MD) is suggested to be one of the causes of Attention Deficit Hyperactivity Disorder. The objective of the study was to evaluate the relationship between MD and ADHD by investigating mitochondrial DNA (mtDNA) levels from peripheral blood leukocytes, one of the best biomarkers of mitochondrial dysfunction. This study included 56 children aged 6-16 years who were diagnosed with ADHD for the first time and 56 age- and sex-matched children without ADHD. Real-time PCR was performed to determine the relative mtDNA copy number in each study participant. The mean mtDNA copy number of the case group was 57.623±24.827 and that of the control group was 44.204±18.926 (p=0.002). The mtDNA copy number of the case group was higher than that of the control group. Results of ROC curve analysis provided a mtDNA cutoff value of 45. Significantly higher mtDNA copy number in ADHD group may suggest mitochondrial dysfunction in the etiopathogenesis of ADHD.