https://www.selleckchem.com/products/XL880(GSK1363089,EXEL-2880).html The findings suggest that perspective-taking plays an important role in the modulation of physiological responses in reaction to attachment-related pictures, which varies according to attachment styles.Purpose To compare the effects of high-load (≥ 70 of 1RM) and low-load ( less then 70 of 1RM) resistance training (RT) on femoral neck and lumbar spine bone mineral density (BMD) in middle-aged and older people. Design Systematic review with meta-analysis. Data source English language searches of the electronic databases PubMed/Medline, Scopus and Web of Science. Inclusion criteria (i) older or middle-aged (≥ 45 years old) participants of both sexes with or without comorbidities, (ii) studies that compared high-load (≥70% 1 RM) versus low-load ( less then 70% 1RM) RT, (iii) studies that examined femoral neck or lumbar spine BMD. Results From 1052 studies found, six were included in qualitative and quantitative analysis. The meta-analysis revealed no difference between groups for femoral neck (weighted mean difference [MD] and 95% confidence interval (CI) = 0.00 g/cm2 [95% CI, -0.01 to 0.01]; P = 0.63) and lumbar spine (MD = 0.01 g/cm2 [95% CI, -0.00 to 0.02]; P = 0.12) BDM. There was a substantial heterogeneity for femoral neck (I2 = 47%; P = 0.07) and lumbar spine (I2 = 59%; P = 0.02). Subgroup analysis revealed a significant effect of high-load RT on femoral neck BMD when participants presented normal BMD values (MD = 0.01 g/cm2 [95% CI, -0.00 to 0.02]; P = 0.04) and on interventions lasting up to 6 months (MD = 0.01 g/cm2 [95% CI, -0.00 to 0.02]; P = 0.03). Conclusion Both high- and low-load RT have similar effects on femoral neck and lumbar spine BMD in aging people.Previous studies indicate that many consumers eat rare hamburgers and that information about microbiological hazards related to undercooked meat does not necessarily lead to changed behavior. With this study we aim to investigate whe