https://www.selleckchem.com/products/indy.html Vascular Ehlers Danlos syndrome is a rare connective tissue disease that is associated with various arterial complications. A 25 year old man with vascular Ehlers Danlos syndrome presented with acute lower back pain as a result of a ruptured aneurysm of the median sacral artery (MSA). Prior medical history included several vascular events resulting in a right iliac occlusion. The unusual location of aneurysmal disease of the MSA might be explained by extensive collateral flow recruitment due to this occlusion. Previous vascular events inducing collateral recruitment might justify a more frequent follow up in patients with connective tissue disorders. Previous vascular events inducing collateral recruitment might justify a more frequent follow up in patients with connective tissue disorders. The combination of endovenous therapies with stab avulsion or ultrasound guided foam sclerotherapy is widely performed. However, these conventional techniques tend to result in incomplete avulsions or persistent varicosities. One hundred and thirteen legs in 97 consecutive patients who underwent 1470 nm laser ablation for great saphenous varicose veins were enrolled. The foam sclerosing agent was injected via the sheath after endovenous laser ablation (EVLA). Patients were divided into two groups EVLA only group (Control; = 50) and EVLA and transluminal injection of foam sclerotherapy (TLFS) group (SCL; = 63). At three month follow up, reflux was abolished throughout all treated great saphenous veins (GSVs) when assessed with Duplex ultrasound. Thrombophlebitis was observed in two patients in the SCL group ( = .13). Additional second stage sclerotherapy was needed in the Control group ( = 33, 66%) SCL group ( = 2, 3%; < .0001). The venous clinical severity score (VCSS) was significantly improved in the SCL group (changes of VCSS, Control-3.3 ± 1.7 and SCL -4.4 ± 1.0; < .0001). Univariable and multivariable analyses revealed that, amo