https://www.selleckchem.com/products/bms-265246.html Qualitative studies investigating weight management experiences are usually cross-sectional or of short duration, which limits understanding of the long-term challenges. Eleven women [mean (SD) age 44.9(9.8)years; body mass index 40.3(4.0)kg m ] participated in this longitudinal qualitative study, which included up to 20weeks of total diet replacement (825-853kcal day ) and ongoing support for weight loss maintenance (WLM), to 2years. Semi-structured interviews were conducted at baseline and programme end, as well as at key intervals during the intervention. Questions examined five theoretical themes motivation, self-regulation, habits, psychological resources and social/environmental influences. Data were coded and analysed in nvivo (https//qsrinternational.com/nvivo) using the framework method. In total, 64 interviews were completed (median, n=6 per participant). Mean (SD) weight loss was 15.7(9.6)kg (14.6% body weight) at 6months and 9.6(9.9)kg (8.8% body weight) at 2years. The prespecified theorhout acknowledging barriers and this may undermine longer-term outcomes. The potential for regain remained over time, mainly as a result of emotion-triggered eating to alleviate stress and negative feelings. More active self-regulation during these circumstances may improve WLM, and these situations represent important targets for intervention.Advance of photonics media is restrained by the lack of structuring techniques for the 3D fabrication of active materials with long-range periodicity. A methodology is reported for the engineering of tunable resonant photonic media with thickness exceeding the plasmonic near-field enhancement region by more than two orders of magnitude. The media architecture consists of a stochastically ordered distribution of plasmonic nanocrystals in a fractal scaffold of high-index semiconductors. This plasmonic-semiconductor fractal media supports the propagation of surface plasmons with dras