https://www.selleckchem.com/products/sivelestat-sodium.html An accurate tumour segmentation in brain images is a complicated task due to the complext structure and irregular shape of the tumour. In this letter, our contribution is twofold (1) a lightweight brain tumour segmentation network (LBTS-Net) is proposed for a fast yet accurate brain tumour segmentation; (2) transfer learning is integrated within the LBTS-Net to fine-tune the network and achieve a robust tumour segmentation. To the best of knowledge, this work is amongst the first in the literature which proposes a lightweight and tailored convolution neural network for brain tumour segmentation. The proposed model is based on the VGG architecture in which the number of convolution filters is cut to half in the first layer and the depth-wise convolution is employed to lighten the VGG-16 and VGG-19 networks. Also, the original pixel-labels in the LBTS-Net are replaced by the new tumour labels in order to form the classification layer. Experimental results on the BRATS2015 database and comparisons with the state-of-the-art methods confirmed the robustness of the proposed method achieving a global accuracy and a Dice score of 98.11% and 91%, respectively, while being much more computationally efficient due to containing almost half the number of parameters as in the standard VGG network.The rapid proliferation of wearable devices for medical applications has necessitated the need for automated algorithms to provide labelling of physiological time-series data to identify abnormal morphology. However, such algorithms are less reliable than gold-standard human expert labels (where the latter are typically difficult and expensive to obtain), due to their large inter- and intra-subject variabilities. Actions taken in response to these algorithms can therefore result in sub-optimal patient care. In a typical scenario where only unevenly sampled continuous or numeric estimates are provided, without access to the "grou