are all frequently associated with absence of corticalization between IMTM root and IAN canal and hence require CBCT examination before surgical extraction is attempted so that post-operative neurological complications can be minimised. Also, Winter's horizontal, distoangular and others as well Pell and Gregory's classes 1B,1C,2A,2B,2C,3A,3B,3C are indicative for CBCT examination before surgical extraction is attempted.  https://www.selleckchem.com/products/oprozomib-onx-0912.html  Fryback and Thornbury model-based comparison proves that CBCT is a better radiographic modality as compared to OPG for evaluation of IMTM relation with IAN canal.Aim The aim of this study is to validate the Fernanda Angelieri classification method for the individual assessment of mid-palatal suture among Indian children using multi-slice computed tomography (CT) with respect to clinical application in rapid maxillary expansion. Material and Methods Present study was conducted utilizing 760 existing head and neck CT image records. CT images were stratified into three categories based on growth spurts Group I - 6-10 years (n = 210), Group II - 11-14 years (n = 270), and Group III - 15-18 years (n = 280). The CT images were analyzed for stages of mid-palatal suture maturation, according to age and sex. The recorded data were subjected for statistical analysis. Results Indian children, up to age of 10 years, were distributed in stage A and B. After 11 years, up to 14 years girls showed varied distribution and spread equally among stage B, C, and D. After 15 years, more number of girls were distributed in stage D and E, whereas boys remained distributed variedly in stage B, C, and D. Mid- palatal suture maturational stages correlated to chronological age among both the genders using Fisher exact test and expected contingency table showed statistically significant variation among both the gender independently and collectively (P less then 0.001). Conclusion Cone beam computed tomography (CBCT)-based prediction of stages of mid- palatal suture maturation by Fernanda Angelieri is valid among the Indian population. During treatment plan of maxillary expansion among children above 10 years, it is better to have a diagnostic CBCT image analysis of mid-palate suture for predicable prognosis.Aim This study aimed to analyze the prevalence of diseases related to pericoronal follicles, and assess the rate of concordance between clinical and histopathological diagnoses. Methods Histologically, we analyzed 1,298 tissue samples surrounding the crowns of teeth that were diagnosed clinically as pericoronal follicles. In addition, we determined associations among histopathological diagnosis, patients' age and sex, tissue site, presence of nests of odontogenic epithelium, presence of reduced enamel epithelium, and presence of diffuse inflammation. Results Odontogenic pathologies were present in 35% of the samples, and rate of concordance between clinical and histopathological diagnoses was 0.54. Probability of developing odontogenic pathologies was high in the mandibular molars (odds ratio 2.13) and in the tissues with odontogenic epithelial remnants (odds ratio 1.2), reduced enamel epithelium (odds ratio 1.3), and diffuse inflammation. (odds ratio 10.5). Conclusions The findings of this study highlight the clinical relevance of histopathological examination of the pericoronal tissue in unerupted and partially erupted teeth for early diagnosis of pathologies because this study demonstrated the odontogenic cysts and inflammatory lesions in tissues clinically diagnosed as pericoronal follicles.Background and Objectives The aciduric mutans streptococci (MS) group, including Streptococcus mutans (SM) and Streptococcus sobrinus (SS), is highly cariogenic. Relationship between increments in dental caries and the presence of these species is not yet clarified. It is of great importance to separately determine the presence of these two species for understanding their role in dental caries, accurate prediction, and effective prevention. Hence, this study was undertaken to detect the presence of SM and SS in plaque samples of caries-free (CF), early childhood caries (ECC), and severe early childhood caries (S-ECC) and also to compare the possible relationship between these species with the occurrence of ECC. Materials and Method In all, 120 healthy children between 3 and 6 years of age were randomly allocated into three groups Group A (n = 40) CF, Group B (n = 40) ECC, and Group C (n = 40) S-ECC. Plaque samples were collected from all approximal surface and gingivobuccal surfaces of teeth using a sterile u S-ECC. There was significant difference between mean dmft/dmfs scores in three study groups and it also showed positive correlation between dmfs scores and SM and SS colonization in ECC and S-ECC status.Introduction One of the most common aesthetic concerns associated with the periodontal tissue is gingival recession. Covering the root surface exposed during the disease process with soft and hard tissue surgeries may decrease these problems. The aim of the study was to compare the clinical outcome of coronally advanced flap (CAF) procedure in root coverage with platelet-rich fibrin (PRF) or subepithelial connective tissue graft (SCTG) for the treatment of Miller's Class-I gingival recession. Materials and Methods The split mouth design consisted of 15 patients with a total of 30 sites with bilateral Miller's Class-I recession on anterior teeth. They were randomly assigned into PRF group (test) or SCTG group (control). Statistical Analysis The values obtained were tabulated and analyzed using Mann--Whitney U-test and repeated measure ANOVA test. All the statistical tests were carried out using SPSS software. Results It was observed that both the autogenous grafts healed without any complications and at the end of 6 months the grafts were stable and recession coverage between 88-100% was achieved. Conclusion CAF procedure with either PRF or SCTG were both effective in the treatment of Miller's Class-I gingival recessions. CAF with SCTG showed better root coverage than CAF with PRF. Use of PRF offered additional benefit of avoiding second surgical site. Therefore, PRF can be considered as a viable alternative to SCTG in certain cases.