In addition, patients of Group 2 at 0 D of defocus curve (infinite) had a visual acuity close to 0 logarithm of the minimum angle of resolution (logMAR) (0.03±0.04). The main outcome of Group 2 defocus curves was that, at defocus point 0 D, even if the mean refraction was -0.67 0.15 × 160, mean unaided logMAR visual acuity was 0.0±0.06. CONCLUSIONS Bilateral monofocal IOLs implanted with mild myopic target provided better intermediate visual acuity compared to emmetropia at a minimal cost in terms of unaided distance visual acuity.A 25-year-old woman with moderate myopia presented for refractive surgery. Bilateral femtosecond laser small-incision lenticule extraction (SMILE) was scheduled and her right eye was completed smoothly.  https://www.selleckchem.com/products/VX-765.html  However, during the lenticule cutting of her left eye, a large inferior black area was noted. The operation was abandoned after an immediate optical coherence tomography examination, which revealed the corneal epithelium defect with no laser scanning line at the corresponding site. The secondary surgery was assigned to laser-assisted subepithelial keratomileusis (LASEK) after 1 week. The uncorrected distance visual acuity of her left eye recovered to 20/25 on the 12 day and to 20/20 at 3-month follow-up, with ideal corneal topography profiles. Corneal epithelium defect induced by accidental alcohol contact during disinfection was suspected to cause the black area. The management of black area had to be determined according to the location and size. LASEK was a rational substitution for the aborted SMILE.Anterior lenticonus is a characteristic ocular feature of Alport syndrome, leading to progressive vision deterioration. Surgical lens removal may be an option in such cases and the role of femtosecond laser assisted cataract surgery (FLACS) has been recently described. Herein we report the third described case, to our knowledge, of bilateral anterior lenticonus surgically approached through FLACS. A 25-year-old male with X-linked Alport syndrome complained of bilateral progressive vision loss. Ophthalmological evaluation revealed a corrected distance visual acuity of 20/63 in both eyes and bilateral anterior lenticonus associated with anterior polar cataract. FLACS was performed followed by intraocular lens placement on the capsular bag, without any intraoperative complications. One month after surgery, uncorrected distance visual acuity was 20/20 in both eyes. Considering these results and the information published so far, this technology might be a good option for these patients.PURPOSE To investigate the accuracy of intraocular lens (IOL) power calculation methods for refractive targets of myopia compared with emmetropia. SETTING Lions Eye Institute, Perth, Australia DESIGN Retrospective analysis. METHODS Patients undergoing bilateral, sequential cataract surgery with a plan of modest monovision were analyzed. Target refraction was plano (distance eye) and -1.25 diopters (D) (near eye). Prediction error was determined by comparing the actual postoperative refraction with the predicted postoperative refraction, calculated by the Barrett Universal II (BUII), Hill-RBF version 2.0 (Hill-RBF 2.0), Haigis, Holladay I, SRK/T, and Hoffer Q formulas. The dataset was divided into distance and near eye subgroups. Mean and median absolute error (MAE; MedAE), and percentage of eyes within +/-0.25, +/-0.50, +/-0.75 and +/-1.00 D of refractive target were compared. RESULTS The study included 88 consecutive patients. There was a consistent trend for lower refractive accuracy in the near eyes. BUII and Hill-RBF 2.0 were the most accurate overall and least affected by this phenomenon, with 1.1% and 4.6% fewer eyes respectively in the near subgroup achieving +/-0.50D of target. Haigis and SRK/T were most affected, with 15.9% and 12.5% fewer near eyes achieving +/-0.50D of target (p less then 0.05). Holladay I and Hoffer Q occupied the middle ground, with 6.8% and 10.2% fewer near eyes achieving +/-0.50D of target. CONCLUSIONS IOL-power calculation formulae appear to be less accurate when targeting myopia compared with emmetropia. BUII and Hill-RBF 2.0 represented good options when planning pseudophakic monovision as they were least affected by this phenomenon and can be used for both distance and near eyes.OBJECTIVES A new bone conduction transducer, the Radioear B-81, has been designed to be an improvement over the commonly used transducer, the Radioear B-71. Reference Equivalent Threshold Force Levels (RETFLs) were obtained with the new Radioear B-81. DESIGN Thresholds were obtained in accordance with ANSI-S3.6-2018 (Annex D) and participants were selected as prescribed in ISO 389.9-2009. Thresholds were obtained with automatic audiometry using circumaural earphones (Radioear DD450) and forehead placement of the bone vibrators. RESULTS Mean bone conduction thresholds obtained using the B-81 and B-71 bone oscillators for frequencies from 250 to 4000 Hz were not statistically different. RETFLs for the B-81 are identical to the values in ANSI S3.6-2018 for the B-71 bone vibrator. Air-bone gaps were observed for both transducers at low frequencies (250 and 500 Hz) due to occlusion effects produced by the circumaural earphone and at high frequencies (3000 and 4000 Hz), previously reported in several studies that used standard RETFLs. Test-retest differences for air conduction thresholds were analyzed and the results are presented in the Appendix A (Supplemental Digital Content 1, http//links.lww.com/EANDH/A639). CONCLUSIONS RETFLs in ANSI S3.6-2018 and ISO 389.3-2016 are appropriate for use with the B-81 bone vibrator.OBJECTIVES The spatial position of a cochlear implant (CI) electrode array affects the spectral cues provided to the recipient. Differences in cochlear size and array length lead to substantial variability in angular insertion depth (AID) across and within array types. For CI-alone users, the variability in AID results in varying degrees of frequency-to-place mismatch between the default electric frequency filters and cochlear place of stimulation. For electric-acoustic stimulation (EAS) users, default electric frequency filters also vary as a function of residual acoustic hearing in the implanted ear. The present study aimed to (1) investigate variability in AID associated with lateral wall arrays, (2) determine the subsequent frequency-to-place mismatch for CI-alone and EAS users mapped with default frequency filters, and (3) examine the relationship between early speech perception for CI-alone users and two aspects of electrode position frequency-to-place mismatch and angular separation between neighboring contacts, a metric associated with spectral selectivity at the periphery.