Dialdehyde polysaccharide (DAP), containing multiple aldehyde groups, can react with materials having amino groups via Schiff base crosslinking. Besides, it can also react with materials having carbonyl/hydroxyl groups via aldol reactions. Based on these intriguing properties, DAPs can be employed as versatile building blocks to fabricate functional materials used in biomedical field, wastewater treatment, leather manufacture, and electrochemistry field. This review aims to provide an overview of the recent advances in fabricating biomaterials, adsorbents, leather tanning agents, and electrochemical materials based on DAPs. The basic fabricating strategy and principle of these materials and their performances are overall summarized, along with a discussion of associated scalability challenges, technological strategies to overcome them, and the prospect for commercial translations of this versatile material. Blending the versatility of DAP with material science and technological advances can provide a powerful tool to develop more DAP-based functional materials in a scalable way.In this work hyaluronic acid (HA) oligosaccharides with degree of polymerization (DP) 4, 6 and 8, obtained by enzymatic depolymerization of HA, were conjugated to a PEG-phospholipid moiety. The products (HA-DP4, HA-DP6 and HA-DP8) were used to prepare decorated liposomes. The cellular uptake of HA-DP4, HA-DP6 and HA-DP8-decorated fluorescently labelled liposomes was significantly higher (12 to 14-fold) in lung cancer cell lines with high CD44 expression than in those with low CD44 expression, suggesting a receptor-mediated entry of HA-conjugated formulations. Competition assays showed that the uptake followed this rank order HA-DP8>HA-DP6>HA-DP4 liposomes. Moreover, they are capable of a faster interaction with CD44, followed by phagocytosis, than HA liposomes obtained from HA of higher molecular weight (4800 and 14800 Da). HA-DP4, HA-DP6 and HA-DP8-liposomes did not show cytotoxicity or inflammatory effects. Overall, we propose our new HA-DP oligosaccharides as biocompatible and effective tools for a potential drug delivery to CD44-positive cells.There is a growing demand for hydrogel-based sensors due to their biomimetic structures and properties, as well as biocompatibility. However, it is still a challenge to fabricate hydrogel sensor with integration of good mechanical properties and high conductivity. Herein, a tough and conductive hydrogel is developed with semi-interpenetrating network formed by incorporating carboxymethyl chitosan and sodium chloride into polyacrylamide network. The hydrogels have high tensile strength, elongation and toughness, but low modulus comparable to human skin. In addition, the hydrogels exhibit fast self-recovery and satisfactory self-healing capabilities. Owing to the existence of sodium chloride, the hydrogel also has high conductivity, good water retention property and anti-freezing ability. When used as a strain sensor, it demonstrates a broad strain window and shows a high sensitivity in monitoring human motions. This work provides a facile method in fabricating multifunctional ionic conductive hydrogel for applications in wearable electronics and soft robotics.Chondroitin sulfate (CS) is one of the major and widespread glycosaminoglycans, a family of structurally complex, linear, anionic hetero-co-polysaccharides. CS plays a vital role in various normal physiological and pathological processes, thus, showing varieties of biological activities, such as anti-oxidation, anti-atherosclerosis, anti-thrombosis, and insignificant immunogenicity. However, the heterogeneity of the naturally occurring CS potentially leads to function unspecific and limits further structure-activity relationship studies. Therefore, the synthesis of CS with well-defined and uniform chain lengths is of major interest for the development of reliable drugs. In this review, we examine the remarkable progress that has been made in the chemical, enzymatic and chemoenzymatic synthesis of CS and its derivatives, providing a broad spectrum of options to access CS of well controlled chain lengths.The depolymerization of biomass carbohydrate polymers usually happened in homogeneous medium, just a few in heterogeneous solution. Herein, holocellulose from two Chinese herb residues Cortex albiziae (HRCA) and Heteropogon contortus (HRHC) was prepared and characterized. Deep eutectic solvent (DES) of choline chloride/p-coumaric acid collaborating with water was employed for the dissociation of those two holocelluloses and selectively dissolved hemicellulose into xylose with maximal yields of 81.50 % and 72.47 %, respectively. Most cellulose remained as the polymer state with a maximum solubility of 9.38 %. The synergistic action of DES and water was investigated to unveil the depolymerization mechanism and the roles of each component in depolymerizing procedure. It was water that released hemicellulose polymers and dissolved polymers to soluble short oligosaccharides, and DES rapidly cleaved the latter to xylose. Contrarily, DES broke cellulose to only soluble cello-oligosaccharides, but water exhibited the ability to hydrolyze cellulose to glucose.Zirconium(IV)-loaded chitosan/Fe3O4/graphene oxide (Zr-CMGO) was fabricated and applied to remove alizarin red (AR) from aqueous solution. Characterizations of Zr-CMGO were performed using several techniques. The effects of initial AR pH, coexisted NaCl, contact time and AR concentration were systematically investigated in batch mode. The increased pH had a negative effect on AR adsorption while there was little impact with salinity.  https://www.selleckchem.com/products/mdivi-1.html  Adsorption capacity toward AR reached up to 231 mg/g at 313 K. The kinetic and isotherm analyses indicated that pseudo-second-order kinetic model and Freundlich model could predicted the uptake of AR. In addition, the mechanism of AR adsorption could be mainly complexation, electrostatic force, etc. There is antibacterial activity from test about Zr-CMGO. Furthermore, the two-stage design could be applied for the theoretical support. Based on all results, Zr-CMGO is a novel and selective adsorbent for practical applications.