WB result showed that serine had a synergistic effect on GPx1 and SEPP expressions as SeMet concentration was 0. 001 μmol/L to 10 μmol/L.
 
  There was an inflection point in selenium protein synthesis when SeMet acted on normal hepatocyte(L02), the specific mechanism needs to be further explored. Secondly, serine had a synergistic effect on GPx1 and SEPP expressions of SeMet in hepatocyte(L02).
 There was an inflection point in selenium protein synthesis when SeMet acted on normal hepatocyte(L02), the specific mechanism needs to be further explored. Secondly, serine had a synergistic effect on GPx1 and SEPP expressions of SeMet in hepatocyte(L02).
  To evaluate the possibility of high-fat diet to induce metabolic syndrome and to alter intestinal development, liver function and intestinal microbiotaof C57 BL/6 J mice.
 
  Total 40 of male C57 BL/6 J aged 3 weeks old were randomly divided into two groups control group and high-fat diet group. After one week of adaptive feeding, the tested mice in high-fat diet group were fed with high-fat diet for 20 weeks, while those in control group were fed with ordinary diet. During the intervention, the body weight of the tested mice was measured weekly and fasting blood glucose(FBG) was measured monthly. Before the end of the experiment, the oral glucose tolerance test(OGTT) of the tested mice was conducted and the fecal 16 S rRNA sequencing was used to profile fecal microbiota of the test mice. Real-time qPCR was used to analyze the concentration of fecal bifidobacteria. Viscera coefficient of liver, spleen and pancreas, visceral fat-body ratio and intestinal length were measured. The indexes of liver function and duce the metabolic syndrome in tested C57 BL/6 J, and lead to the damage of intestinal development, abnormality of liver tissue and its function, decrease diversity of intestinal microbiota, and the transformation of intestinal microbiota community to obesity type.
 High-fat diet could induce the metabolic syndrome in tested C57 BL/6 J, and lead to the damage of intestinal development, abnormality of liver tissue and its function, decrease diversity of intestinal microbiota, and the transformation of intestinal microbiota community to obesity type.
  To observe the effects of swimming training and/or epigallocatechin gallate(EGCG) on the expression of myocardial interstitial protein and its relationship with transforming growth factor-beta(TGF-β)/Smads signaling pathway in type 2 diabetic rats.
 
  Male SD rats(SPF grade, 6 weeks old) were fed with high-fat diet for 6 weeks and intraperitoneal injection of streptozotocin(STZ, 30 mg/kg). The rats were randomly divided into four groups diabetic model group(D), diabetes EGCG group(DG), diabetes exercise group(DE), and diabetes exercise EGCG group(DEG), with 8 rats in each group, and 6 male SD rats in the same batch were added as the normal C group. The rats in the exercise group were given swimming training without load. The swimming time was 15 min/d in the first week, and the time was increased by 15 min a week until it was extended to 90 min/d. The rats in the exercise group were trained for 5 days a week. Rats in the EGCG group(100 mg/kg BW) were intragastrical administered for 7 days. Swimming training the expression of myocardial interstitial protein in type 2 diabetic rats, and the combined intervention effect is better.
  To detect the concentrations of ten metals and metalloid elements in the atmospheric PM_(2. 5) in Chengguan district and Xigu district of Lanzhou City from 2015 to 2018, and analyze the pollutant concentration and its change trend.
 
  From 2015 to 2018, 662 samples of PM_(2. 5) were collected from Chengguan district and Xigu district of Lanzhou City. The concentrations of 10 kinds of metals and metalloid elements such as lead(Pb), arsenic(As), mercury(Hg), cadmium(Cd), chromium(Cr), antimony(Sb), manganese(Mn), nickel(Ni), selenium(Se), beryllium(Be) were detected, and the change trends of different monitoring points, years, seasons and months were analyzed.
 
  There was a significant difference in lead content between Chengguan District and Xigu District(χ~2=4. 80, P<0. 05), the median of Pb content in Chengguan and Xigu District was 45. 30 and 37. 20 ng/m~3, which was higher than that in Xigu District; the difference of Mn content in the two districts was statistically significant(χ~2=21. 28, P&l, and the content of other elements showed a significant seasonal change winter>spring>autumn> summer. The trend of monthly concentration change in the two regions was basically the same, the concentrations of Sb, As, Pb, Mn, Cd, Ni, Se, Hg and Cr were higher in November and February of next year. In Chengguan District and Xigu District, Ni content was higher in July and August, respectively;and Hg in Xigu District was higher in June, and Be was higher in less months, especially in February, October and December.
 
  From 2015 to 2018, the levels of 10 metals and metalloids element pollutants in PM_(2. 5) samples from Chengguan District and Xigu District of Lanzhou City showed a decreasing trend year by year, and had obvious seasonal changes.
 From 2015 to 2018, the levels of 10 metals and metalloids element pollutants in PM_(2. 5) samples from Chengguan District and Xigu District of Lanzhou City showed a decreasing trend year by year, and had obvious seasonal changes.
  To investigate the occurrence data for fatty acid esters of chloropropanol and glycidyl in edible vegetable oils purchased in China.
 
  The 1309 samples of edible vegetable oil were collected and the data of chloropropanol and glycidyl were detected by the gas chromatography-mass spectrometry from 2015 to 2017.
 
  The detection rate of 3-monochloropropanediol esters in vegetable oils was 81. 83% with the mean level of 1. 21 mg/kg. The mean content of tea-seed oil was significantly higher than that of other varieties, followed by peanut oil(1.  https://www.selleckchem.com/products/fht-1015.html  36 mg/kg), rapeseed oil(1. 12 mg/kg). The sunflower seed oil has the lowest mean content(0. 54 mg/kg). The detection rate of 2-monochloropropanediol esters in vegetable oils was 82. 84% with the mean level of 0. 39 mg/kg. The content of peanut oil was significantly higher than that of other varieties, followed by blended oil(0. 30 mg/kg) and soybean oil(0. 25 mg/kg). There was no significant difference with rapeseed oil(0. 66 mg/kg). The exceeding rate of glycidyl ester was 19.