es fiscal policies, social protection, labor market, and employment policies need to improve education and wealth status for women from poor households. This might be the first step toward achieving universal maternal health coverage.Intimate and sexual relationships provide opportunity for emotional and sexual fulfillment. In consensually non-monogamous (CNM) relationships, needs are dispersed among multiple partners. Using Self-Determination Theory (SDT) and dyadic data from 56 CNM partnerships (112 individuals), we tested how sexual motives and need fulfillment were linked to relational outcomes. We drew from models of need fulfillment to explore how sexual motives with a second partner were associated with satisfaction in the primary relationship. In a cross-sectional and daily experience study we demonstrated that self-determined reasons for sex were positively associated with sexual satisfaction and indirectly linked through sexual need fulfillment. Self-determined reasons for sex predicted need fulfillment for both partners at a three-month follow up. The association between sexual motives and need fulfillment was stronger on days when participants engaged in sex with an additional partner, though this was not related to satisfaction in the primary relationship. Implications for need fulfillment are discussed.
  Beta-blocker (BB) is suggested to have anticancer efficacy. However, the potential influence of BB use on overall survival (OS) in patients with lung cancer remains undetermined. We aimed to evaluate the above relationship in an updated meta-analysis.
 
  Observational studies comparing OS between users and non-users of BB with lung cancer were identified by search of PubMed, Embase, and Cochrane's Library. A random-effect model was used to pool the results.
 
  Ten retrospective cohort studies with 30870 patients were included. Overall, BB use was not associated with significantly improved OS in lung cancer (hazard ratio [HR] = 1.02, 95% confidence interval [CI] 0.98 to 1.06, p = 0.33) with moderate heterogeneity (I2 = 29%). Stratified analyses showed similar results in patients with non-small cell lung cancer and small cell lung cancer, in studies with BB use before and after the diagnosis of lung cancer, and in studies with or without adjustment of smoking. Use of BB was associated with improved OS in patients with stage III lung cancer (HR = 0.91, 95% CI 0.85 to 0.98, p = 0.02) and in patients that did not receive surgery resection (HR = 0.78, 95% CI 0.64 to 0.96, p = 0.02), while use of non-selective BB was associated with worse OS (HR = 1.14, 95% CI 1.01 to 1.28, p = 0.03).
 
  This meta-analysis of retrospective cohort studies does not support a significant association between BB use and improved OS in lung cancer.
 This meta-analysis of retrospective cohort studies does not support a significant association between BB use and improved OS in lung cancer.During the Covid-19 pandemic, universities in the UK used social media to raise awareness and provide guidance and advice about the disease to students and staff. We explain why some universities used social media to communicate with stakeholders sooner than others. To do so, we identified the date of the first Covid-19 related tweet posted by each university in the country and used survival models to estimate the effect of university-specific characteristics on the timing of these messages. In order to confirm our results, we supplemented our analysis with a study of the introduction of coronavirus-related university webpages.  https://www.selleckchem.com/products/AZD2281(Olaparib).html  We find that universities with large numbers of students are more likely to use social media and the web to speak about the pandemic sooner than institutions with fewer students. Universities with large financial resources are also more likely to tweet sooner, but they do not introduce Covid-19 webpages faster than other universities. We also find evidence of a strong process of emulation, whereby universities are more likely to post a coronavirus-related tweet or webpage if other universities have already done so.Drawing on fine particulate matter (PM2.5) from satellite raster data and matching with the county-level socio-economic data from 2008 to 2015 in China, this paper investigates the impacts of the establishment of National Key Ecological Functional Zones (NKEFZ) on environmental quality by employing the difference-in-differences method, which was stablished in June 2011. The results indicate that the establishment of the NKEFZ significantly decreased the concentration values of PM2.5, a drop of about 20% during the study period, after the paper controls for other factors affecting air quality. The robustness tests using the maximum and medium concentration values of PM2.5 show similar results. Through further analysis, the paper finds that the establishment of NKEFZ can improve the ecological utilization efficiency of land.A pervasive issue in statistical learning has been to determine the parameters of regularity extraction. Our hypothesis was that the extraction of transitional probabilities can prevail over frequency if the task involves prediction. Participants were exposed to four repeated sequences of three stimuli (XYZ) with each stimulus corresponding to the position of a red dot on a touch screen that participants were required to touch sequentially. The temporal and spatial structure of the positions corresponded to a serial version of the exclusive-or (XOR) that allowed testing of the respective effect of frequency and first- and second-order transitional probabilities. The XOR allowed the first-order transitional probability to vary while being not completely related to frequency and to vary while the second-order transitional probability was fixed (p(Z|X, Y) = 1). The findings show that first-order transitional probability prevails over frequency to predict the second stimulus from the first and that it also influences the prediction of the third item despite the presence of second-order transitional probability that could have offered a certain prediction of the third item. These results are particularly informative in light of statistical learning models.