https://www.selleckchem.com/products/gsk503.html GSEA revealed the functional and pathway enrichment of these seven MRGs. Then, drug sensitivity analysis indicated that G6PD might play a key role in the prognosis of HCC by promoting chemoresistance. Finally, we used IHC staining to demonstrate the relationship between G6PD expression levels and clinical parameters in HCC patients. The results of this study provide a potential method for predicting the prognosis of HCC patients and avenues for further studies of HCC metabolism. Moreover, the function of G6PD may play a key role in the development and progression of HCC. The results of this study provide a potential method for predicting the prognosis of HCC patients and avenues for further studies of HCC metabolism. Moreover, the function of G6PD may play a key role in the development and progression of HCC. Breast cancer is the second most common cancer in women globally, and the incidence rate has increased annually. Traditional medicine is frequently used as a cancer treatment, and soursop or L ( ) is a traditional medicinal plant that has been widely used as an anticancer treatment and requires more thorough study. In this research, we prepared ethanol extract and three solvents, ie, ethyl acetate, -hexane and water fractions of leaves and assessed their antiproliferation and cytotoxic activity on MCF7 breast cancer cells compared with that on CV1 normal kidney cells; observation of cell morphology by stained with mixture of propidium iodide and 4',6-diamidino-2-phenylindole indicated that this treatment induced an ongoing process of apoptotic cell death in MCF7 cells. To clarify the cell death mechanism via apoptosis, we assessed the expression in the caspase cascade of , and , and anti-apoptotic, which mediated cytotoxic activity of extracts and ethyl acetate fractions of leaves agnticancer treatment for breast cancer via induced apoptotic cell death. Globally, hypertension is becoming a serious problem affecti