https://www.selleckchem.com/products/U0126.html The SNOT-22 (22-item Sinonasal Outcome Test) is a high-quality outcome measure that assesses chronic rhinosinusitis-specific quality of life. The aim of this study was to gain greater insight into the information provided by the SNOT-22 by determining its item-based psychometric properties. Retrospective cohort study. Tertiary care academic centers. This study used a previously described data set of the SNOT-22 completed by 800 patients with chronic rhinosinusitis. Item response theory graded response models were used to determine parameters reflecting item discrimination, difficulty, and information provided by each item toward the SNOT-22 subdomain to which it belonged. The unconstrained graded response model fitted the SNOT-22 data best. Item discrimination parameters and total information provided showed the greatest variability within the nasal subdomain, and the item related to sense of smell/taste demonstrated the lowest discrimination and provided the least amount of information overall. Therent levels of disease burden.The widespread use of digital technology and devices has fundamentally transformed people's social life in recent decades, particularly in interpersonal relationships. Two popular social phenomena elucidate how social connections and interactions have dramatically evolved due to technological advancement. Sexting has surfaced as a popular way of getting attention or flirting among young populations over the past decade. Online dating also has emerged as a viable avenue for people to seek interpersonal romantic and/or sexual relationships. Based on survey data collected from two Chinese universities and one U.S. university, this study links sexting and online dating by comparatively assessing the prevalence of sexting victimization and factors influencing such victimization among young online daters. Bivariate and multiple analyses reveal that American college students are more inclined than thei