https://www.selleckchem.com/products/ABT-263.html Along with other discoveries, these findings form the basis of our current understanding of MEAD. Bamboo nodes are transverse creamy-yellow subepithelial nodes in the vocal folds (VF) midpoint, usually bilateral, resembling a bamboo stem. They appear almost exclusively in females, and are associated with underlying autoimmune diseases. Six female patients, 45.5 years median age, with underlying autoimmune diseases, consulted due to dysphonia. The laryngeal stroboscopy showed bilateral VF bamboo nodes in four patients, and unilateral in the remaining two. VF mobility was normal in all patients, while the mucosal wave was impaired in four of them. Treatment with speech therapy and proton pump inhibitors was indicated. All the patients were referred for rheumatologic evaluation and immunosuppressive treatment optimization. Follow-up in five patients showed vocal function self-perception and GRBAS scores improvement. VF bamboo nodes are an infrequent cause for dysphonia, associated with phonotrauma and autoimmune diseases. Speech therapy and a rheumatologic workup must be indicated, for immunosuppressive treatment enhancement. VF bamboo nodes are an infrequent cause for dysphonia, associated with phonotrauma and autoimmune diseases. Speech therapy and a rheumatologic workup must be indicated, for immunosuppressive treatment enhancement.Surgical correction of a flatfoot deformity is controversial. The purpose of our study was to evaluate the structural radiographic changes of the flatfoot deformity while maintaining the mobile adapter of the foot. We conducted a retrospective analysis of 56 patients that underwent this procedure comparing their pre- to postoperative angular changes during a follow-up period. The mean age of our study cohort was 53.6 (range, 20-77) years and mean follow-up period was 23 (range, 4-73) months. Radiographic union was achieved in 48 patients (86%). Forty-six patients (82%) had all required rad