https://www.selleckchem.com/products/wm-1119.html 034) correlated significantly with inverted discordant p57 staining. Other common features of DCV with inverted discordant p57 expression include larger villous size compared with surrounding tertiary villi (13/17, 76.4%), prominent but not hyperplastic and focally to moderately hyperplastic syncytiotrophoblast (17/21, 80.9%), abnormal shapes/irregular contours (17/22, 77.3%), and markedly hypovascular villous stroma (11/17, 64.7%). No distinctive maternal or fetal features were observed. Inverted discordant p57 expression in DCV of third trimester placentas is likely underreported, and might not be an unusual occurrence outside of suspected molar specimens. Inverted discordant p57 expression in DCV of third trimester placentas is likely underreported, and might not be an unusual occurrence outside of suspected molar specimens.The forensic fingerprint community has faced increasing criticism by scientific and legal commentators, challenging the validity and reliability of fingerprint evidence due to the lack of an empirical basis to assess the quality of the friction ridge impressions. This paper presents a method, developed as a stand-alone software application, DFIQI ("Defense Fingerprint Image Quality Index"), which measures the clarity of friction ridge features (locally) and evaluates the quality of impressions (globally) across three different scales value, complexity, and difficulty. Performance was evaluated using a variety of datasets, including datasets designed to simulate casework and a dataset derived directly from casework under operational conditions. The results show performance characteristics that are consistent with experts' subjective determinations. This method provides fingerprint experts (1) a more rigorous approach by providing an empirical foundation to support their subjective determinations from the Analysis phase of the examination methodology, (2) a framework for organizations to establis